Ion Mobility Mass Spectrometry As an Efficient Tool for Identification of Streptorubin B in M145

Overview

Journal J Nat Prod

Date 2020 Jan 7

PMID 31904955

Citations 3

Authors

Andrew P Marshall

Andrew R Johnson

Marvin M Vega

Regan J Thomson

Erin E Carlson

Affiliations

Soon will be listed here.

Abstract

Ion mobility spectrometry was utilized to corroborate the identity of streptorubin B () as the natural product produced by . Natural product was initially assigned as butylcycloheptylprodigiosin (), and only relatively recently was this assignment clarified. We present additional evidence of this assignment by comparing collisional cross sections (Ω) of synthetic standards of , , and metacycloprodigiosin () to the cyclic prodiginine produced by . Calculated theoretical Ω values demonstrate that cyclic prodiginines could be identified without standards. This work highlights ion mobility as an efficient tool for the dereplication of natural products.

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