Bioactivities of Leaf Extracts Conjugated with Zinc Oxide Nanoparticles

Overview

Journal Biomolecules

Publisher MDPI

Specialties Biochemistry
Molecular Biology

Date 2020 Jan 1

PMID 31888037

Citations 25

Authors

Banzeer Ahsan Abbasi

Javed Iqbal

Riaz Ahmad

Layiq Zia

Sobia Kanwal

Tariq Mahmood

Canran Wang

Jen-Tsung Chen

Affiliations

Soon will be listed here.

Abstract

This study attempts to obtain and test the bioactivities of leaf extracts from a medicinal plant, (GW), when conjugated with zinc oxide nanoparticles (ZnONPs). The integrity of leaf extract-conjugated ZnONPs (GW-ZnONPs) was confirmed using various techniques, including Ultraviolet-visible spectroscopy, X-Ray Diffraction, Fourier Transform Infrared Spectroscopy, energy-dispersive spectra (EDS), scanning electron microscopy, transmission electron microscopy, and Raman spectroscopy. The size of ZnONPs was approximately 18 nm, which was determined by TEM analysis. Additionally, the energy-dispersive spectra (EDS) revealed that NPs have zinc in its pure form. Bioactivities of GW-ZnONPs including antimicrobial potentials, cytotoxicity, antioxidative capacities, inhibition potentials against α-amylase, and protein kinases, as well as biocompatibility were intensively tested and confirmed. Altogether, the results revealed that GW-ZnONPs are non-toxic, biocompatible, and have considerable potential in biological applications.

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