Incidence, Management, Prevention and Outcome of Post-Operative Atrial Fibrillation in Thoracic Surgical Oncology

Overview

Journal J Clin Med

Specialty General Medicine

Date 2019 Dec 28

PMID 31878032

Citations 5

Authors

Iacopo Fabiani

Alessandro Colombo

Giulia Bacchiani

Carlo Maria Cipolla

Daniela Maria Cardinale

Affiliations

Soon will be listed here.

Abstract

Atrial fibrillation (AF) is a common supraventricular arrhythmia, a recognized risk factor for ischemic stroke, as a potential driver for heart failure (HF). Cancer patients have an increased risk for AF, even not including any cancer-specific treatment, as surgery or chemotherapy. The mechanism is multifactorial, with inflammation and changes in autonomic tone as critical actors. Commonly, AF is a recurrent complication of the post-operative period in cancer surgery (especially thoracic). Recent papers confirmed a significant incidence of post-operative (non-cardiac surgery) AF (PAF), partially mitigated by the use of prophylactic (rate o rhythm control) treatments. A relevant difference, in terms of mean hospitalization time, emerges between patients developing PAF and those who do not, while long term impact remains a matter of debate, due to several potential confounding factors. Besides clinical predictors, structural (i.e., echocardiographic) and bio-humoral findings may help in risk prediction tasks. In this respect, pre-operative natriuretic peptides (NPs) concentrations are nowadays recognized as significant independent predictors of perioperative cardiovascular complications (including PAF), while elevated post-operative levels may further enhance risk stratification. The aim of the present paper is to trace the state of the art in terms of incidence, management, prevention, and outcome of PAF in the field of thoracic surgical oncology.

Citing Articles

Atrial Fibrillation and Cancer-Epidemiology, Mechanisms, and Management.

Davis N, Prasitlumkum N, Tan N J Clin Med. 2025; 13(24.

PMID: 39768676 PMC: 11677472. DOI: 10.3390/jcm13247753.

Crosslink between atrial fibrillation and cancer: a therapeutic conundrum.

Nardi E, Santoro C, Prastaro M, Canonico M, Paolillo S, Gargiulo G Cardiooncology. 2024; 10(1):48.

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Prevention of new-onset atrial fibrillation in elderly patients undergoing anatomic pulmonary resection by infusion of magnesium sulfate: protocol for a randomized controlled trial.

Jin S, An L, Chen L, Liu H, Chen H, Lv X Front Cardiovasc Med. 2023; 10:1171713.

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Current Data and Future Perspectives on Patients with Atrial Fibrillation and Cancer.

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