Beliefs of UK Transplant Recipients About Living Kidney Donation and Transplantation: Findings from a Multicentre Questionnaire-Based Case-Control Study

Overview

Journal J Clin Med

Specialty General Medicine

Date 2019 Dec 28

PMID 31877750

Citations 3

Authors

Pippa K Bailey

Fergus J Caskey

Stephanie Macneill

Charles Tomson

Frank J M F Dor

Yoav Ben-Shlomo

Affiliations

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Abstract

Differing beliefs about the acceptability of living-donor kidney transplants (LDKTs) have been proposed as explaining age, ethnic and socioeconomic disparities in their uptake. We investigated whether certain patient groups hold beliefs incompatible with LDKTs. This questionnaire-based case-control study was based at 14 hospitals in the United Kingdom. Participants were adults transplanted between 1 April 2013 and 31 March 2017. LDKT recipients were compared to deceased-donor kidney transplant (DDKT) recipients. Beliefs were determined by the direction and strength of agreement with ten statements. Multivariable logistic regression was used to investigate the association between beliefs and LDKT versus DDKT. Sex, age, ethnicity, religion, and education were investigated as predictors of beliefs. A total of 1240 questionnaires were returned (40% response). DDKT and LDKT recipients responded in the same direction for 9/10 statements. A greater strength of agreement with statements concerning the 'positive psychosocial effects' of living kidney donation predicted having an LDKT over a DDKT. Older age, Black, Asian and Minority Ethnic (BAME) group ethnicity, and having a religion other than Christianity were associated with greater degree of uncertainty regarding a number of statements, but there was no evidence that individuals in these groups hold strong beliefs against living kidney donation and transplantation. Interventions should address uncertainty, to increase LDKT activity in these groups.

Citing Articles

Living Donor Kidney Transplantation in Older Individuals: An Ethical Legal and Psychological Aspects of Transplantation (ELPAT) View.

Courtney A, Moorlock G, Van Assche K, Burnapp L, Mamode N, Lennerling A Transpl Int. 2023; 36:11139.

PMID: 37152615 PMC: 10161899. DOI: 10.3389/ti.2023.11139.

Investigating Ethnic Disparity in Living-Donor Kidney Transplantation in the UK: Patient-Identified Reasons for Non-Donation among Family Members.

Wong K, Owen-Smith A, Caskey F, Macneill S, Tomson C, Dor F J Clin Med. 2020; 9(11).

PMID: 33233422 PMC: 7700269. DOI: 10.3390/jcm9113751.

Recent Advances and Clinical Outcomes of Kidney Transplantation.

Thongprayoon C, Hansrivijit P, Leeaphorn N, Acharya P, Torres-Ortiz A, Kaewput W J Clin Med. 2020; 9(4).

PMID: 32331309 PMC: 7230851. DOI: 10.3390/jcm9041193.

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