Effect of a Persian Medicine Preparation, , on Constipation in Patients with Hypertension

Overview

Journal J Res Med Sci

Specialty General Medicine

Date 2019 Dec 19

PMID 31850089

Citations 1

Authors

Maryam Navabzadeh

Fataneh Hashem-Dabaghian

Toba Kazemi

Asie Shojaii

Iman Nakhaei

Javad Hadinia

Roshanak Ghods

Affiliations

Soon will be listed here.

Abstract

Background: Constipation is a common and prevalent digestive problem. Forcing and straining due to constipation may have a negative effect on some parts of the body, including the heart. The aim of the study was to evaluate the effect of (a kind of whey) on functional constipation in hypertensive patients.

Materials And Methods: The present double-blind, placebo-controlled randomized clinical trial was a part of the study about the effect of on stage 1 hypertension, performed in 2017-2018. Hypertensive patients accompanying constipation were included in the study. Patients were randomly divided into two groups: Group A ( = 19) received 25 g of powder and Group B ( = 22) received 25 g of maltodextrin powder, twice a day for 6 weeks. The number and quality of defecation during a day were evaluated at baseline and at the end of the study within and between groups. Data were analyzed by SPSS software (version: 17) using Chi-square or Fisher's exact test. <0.05 was considered as significant level.

Results: Forty-one patients had inclusion criteria, of whom 34 patients completed the study (19 in Group A and 15 in Group B). The mean ± standard deviation age of patients was 53.86 ± 8.92 years (range: 34-80 years). Before intervention, there was no significant difference between the two groups with respect to constipation; however, after 6 weeks' treatment, the frequency of constipation was significantly different between groups ( < 0.001). At the end of 6 week, constipation in the Group A was improved completely in terms of the number of defecation and stool consistency; but, in the Group B, eight (53.33%) patients still suffered from constipation ( < 0.001). No specific complications were reported in both groups.

Conclusion: can improve constipation in hypertensive patients without any adverse effect.

Citing Articles

Efficacy of Ma'aljobon Aftimouni ( and whey) on HbA1c and blood glucose levels in patients with Type 2 Diabetes: A randomized triple-blind clinical trial.

Mehrabi F, Safdari A, Moslemi A, Salehi M, Agharazi A, Rezvanfar M Contemp Clin Trials Commun. 2025; 43:101401.

PMID: 39742327 PMC: 11683214. DOI: 10.1016/j.conctc.2024.101401.

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