» Articles » PMID: 31842504

Cytomegalovirus Seropositivity and Suicidal Behavior: A Mini-Review

Overview
Publisher MDPI
Specialty General Medicine
Date 2019 Dec 18
PMID 31842504
Citations 1
Authors
Affiliations
Soon will be listed here.
Abstract

In recent years, a growing body of research has focused on identifying possible biological markers for suicidal behavior, including infective and immunological markers. In this paper, our aim was to review available evidence concerning the association between cytomegalovirus (CMV) infection and suicide. A systematic search according to the PRISMA statement was performed on Pubmed. After the screening procedure, we identified five relevant papers. We found inconsistent evidence linking CMV infection and suicide, with some papers reporting an association between CMV seropositivity and suicidal behavior, and others not finding the association. With the evidence available presently, it is not possible to infer whether there is a correlation between suicide and CMV infection.

Citing Articles

Spanish HCMV Seroprevalence in the 21st Century.

Alvarez-Heredia P, Reina-Alfonso I, Dominguez-Del-Castillo J, Hassouneh F, Gutierrez-Gonzalez C, Batista-Duharte A Viruses. 2024; 16(1).

PMID: 38275940 PMC: 10819642. DOI: 10.3390/v16010006.

References
1.
Dollard S, Grosse S, Ross D . New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Rev Med Virol. 2007; 17(5):355-63. DOI: 10.1002/rmv.544. View

2.
Hawkins-Villarreal A, Moreno-Espinosa A, Eixarch E, Marcos M, Martinez-Portilla R, Salazar L . Blood parameters in fetuses infected with cytomegalovirus according to the severity of brain damage and trimester of pregnancy at cordocentesis. J Clin Virol. 2019; 119:37-43. DOI: 10.1016/j.jcv.2019.08.008. View

3.
Zhang Y, Traskman-Bendz L, Janelidze S, Langenberg P, Saleh A, Constantine N . Toxoplasma gondii immunoglobulin G antibodies and nonfatal suicidal self-directed violence. J Clin Psychiatry. 2012; 73(8):1069-76. DOI: 10.4088/JCP.11m07532. View

4.
Burgdorf K, Trabjerg B, Pedersen M, Nissen J, Banasik K, Pedersen O . Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders. Brain Behav Immun. 2019; 79:152-158. DOI: 10.1016/j.bbi.2019.01.026. View

5.
Suzuki H, Ohgidani M, Kuwano N, Chretien F, de la GrandMaison G, Onaya M . Suicide and Microglia: Recent Findings and Future Perspectives Based on Human Studies. Front Cell Neurosci. 2019; 13:31. PMC: 6381042. DOI: 10.3389/fncel.2019.00031. View