Metabolic Syndrome and Skin Diseases

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2019 Dec 12

PMID 31824416

Citations 31

Authors

Yu Hu

Yun Zhu

Ni Lian

Min Chen

Andrzej Bartke

Rong Yuan

Affiliations

Soon will be listed here.

Abstract

The increasing prevalence of Metabolic syndrome (MetS) is a worldwide health problem, and the association between MetS and skin diseases has recently attracted growing attention. In this review, we summarize the associations between MetS and skin diseases, such as psoriasis, acne vulgaris, hidradenitis suppurativa, androgenetic alopecia, acanthosis nigricans, and atopic dermatitis. To discuss the potential common mechanisms underlying MetS and skin diseases, we focus on insulin signaling and insulin resistance, as well as chronic inflammation including adipokines and proinflammatory cytokines related to molecular mechanisms. A better understanding of the relationship between MetS and skin diseases contributes to early diagnosis and prevention, as well as providing clues for developing novel therapeutic strategies.

Citing Articles

The interplay of factors in metabolic syndrome: understanding its roots and complexity.

Islam M, Wei P, Suzauddula M, Nime I, Feroz F, Acharjee M Mol Med. 2024; 30(1):279.

PMID: 39731011 PMC: 11673706. DOI: 10.1186/s10020-024-01019-y.

Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis.

Zhang S, Yan H, Sun W, Li J, Xu J, Cao D Skin Res Technol. 2024; 30(9):e70054.

PMID: 39258800 PMC: 11388607. DOI: 10.1111/srt.70054.

Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions.

Anitua E, Tierno R, Azkargorta M, Elortza F, Alkhraisat M Biomolecules. 2024; 14(7).

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Exploring the pathogenesis and immunological profiles of psoriasis complicated with MASLD.

Tan S, Liu M, Feng F, Li R, Tian R, Nie Z PLoS One. 2024; 19(6):e0305217.

PMID: 38917217 PMC: 11198785. DOI: 10.1371/journal.pone.0305217.

[Screening for Characteristic Genes of Different Traditional Chinese Medicine Syndromes of Psoriasis Vulgaris: A Study Based on Bioinformatics and Machine Learning].

Liu X, Jia H, Wang L, Wang Z, Xu M, Li Y Sichuan Da Xue Xue Bao Yi Xue Ban. 2024; 55(2):337-345.

PMID: 38645867 PMC: 11026890. DOI: 10.12182/20240360402.

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