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Challenging Scenarios in Nontuberculous Mycobacterial Infection in Cystic Fibrosis

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Date 2019 Dec 11
PMID 31821718
Citations 4
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Abstract

This review summarizes the discussion of a session held during the 2018 North American Cystic Fibrosis (CF) Conference titled "Challenging Cases in Nontuberculous Mycobacterial (NTM) Management." In this session, a multidisciplinary panel of NTM experts discussed clinical challenges related to the management of NTM infection in people with CF in which decision-making falls outside of the Cystic Fibrosis Foundation/European Cystic Fibrosis Society NTM guidelines. Topics discussed included managing newly acquired NTM infection, selecting and monitoring treatment regimens, determining treatment endpoints, and caring for patients after NTM treatment.

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References
1.
Gilljam M, Berning S, Peloquin C, Strandvik B, Larsson L . Therapeutic drug monitoring in patients with cystic fibrosis and mycobacterial disease. Eur Respir J. 1999; 14(2):347-51. DOI: 10.1034/j.1399-3003.1999.14b18.x. View

2.
Griffith D, Aksamit T, Brown-Elliott B, Catanzaro A, Daley C, Gordin F . An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007; 175(4):367-416. DOI: 10.1164/rccm.200604-571ST. View

3.
Floto R, Olivier K, Saiman L, Daley C, Herrmann J, Nick J . US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis. Thorax. 2015; 71 Suppl 1:i1-22. PMC: 4717371. DOI: 10.1136/thoraxjnl-2015-207360. View

4.
Ronchetti K, Tame J, Paisey C, Thia L, Doull I, Howe R . The CF-Sputum Induction Trial (CF-SpIT) to assess lower airway bacterial sampling in young children with cystic fibrosis: a prospective internally controlled interventional trial. Lancet Respir Med. 2018; 6(6):461-471. PMC: 5971213. DOI: 10.1016/S2213-2600(18)30171-1. View

5.
Esther Jr C, Kerr A, Gilligan P . Detection of Mycobacterium abscessus from deep pharyngeal swabs in cystic fibrosis. Infect Control Hosp Epidemiol. 2015; 36(5):618-9. DOI: 10.1017/ice.2015.40. View