Neuroimaging Methods for Nursing Science

Overview

Journal Nurs Res

Specialty Nursing

Date 2019 Dec 6

PMID 31804432

Citations 4

Authors

Sebastian W Atalla

Laura Beth Kalvas

Jenna L Campbell

Alison R Anderson

Ronald L Cowan

Kathy Wright

Angela C Humbel

Todd B Monroe

Affiliations

Soon will be listed here.

Abstract

Background: Since the inception of magnetic resonance imaging, thousands of studies have appeared in the literature reporting on multiple imaging techniques. However, there is a paucity of neuroimaging research programs developed by nurse scientists.

Objectives: The purpose of this article is to introduce the nurse scientist to complex neuroimaging methods with the ultimate goal of creating impetus for future use of brain imaging in nursing research.

Methods: This article reviews common neuroimaging methods, presents vocabulary frequently used in neuroimaging work, provides information on access to resources in neuroimaging education, and discusses considerations for use of neuroimaging in research.

Results: Ten imaging modalities are reviewed, including structural and functional magnetic resonance imaging, computed tomography, positron emission tomography, and encephalography.

Discussion: Choosing an imaging modality for research depends on the nature of the research question, needs of the patient population of interest, and resources available to the novice and seasoned nurse scientist. Neuroimaging has the potential to innovate the study of symptom science and encourage interdisciplinary collaboration in research.

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References

Kwong K, Belliveau J, Chesler D, Goldberg I, Weisskoff R, Poncelet B . Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci U S A. 1992; 89(12):5675-9. PMC: 49355. DOI: 10.1073/pnas.89.12.5675. View

Hutchinson A, Johnston L . Bridging the divide: a survey of nurses' opinions regarding barriers to, and facilitators of, research utilization in the practice setting. J Clin Nurs. 2004; 13(3):304-15. DOI: 10.1046/j.1365-2702.2003.00865.x. View

Biswal B, Yetkin F, Haughton V, Hyde J . Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med. 1995; 34(4):537-41. DOI: 10.1002/mrm.1910340409. View

Alsop D, Detre J, Golay X, Gunther M, Hendrikse J, Hernandez-Garcia L . Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med. 2014; 73(1):102-16. PMC: 4190138. DOI: 10.1002/mrm.25197. View

Lopes da Silva F . EEG and MEG: relevance to neuroscience. Neuron. 2013; 80(5):1112-28. DOI: 10.1016/j.neuron.2013.10.017. View

Wang J, Zuo X, He Y . Graph-based network analysis of resting-state functional MRI. Front Syst Neurosci. 2010; 4:16. PMC: 2893007. DOI: 10.3389/fnsys.2010.00016. View

Berger A . How does it work? Positron emission tomography. BMJ. 2003; 326(7404):1449. PMC: 1126321. DOI: 10.1136/bmj.326.7404.1449. View

Wattjes M . Structural MRI. Int Psychogeriatr. 2011; 23 Suppl 2:S13-24. DOI: 10.1017/S1041610211000913. View

M Soares J, Marques P, Alves V, Sousa N . A hitchhiker's guide to diffusion tensor imaging. Front Neurosci. 2013; 7:31. PMC: 3594764. DOI: 10.3389/fnins.2013.00031. View

10.

Forster B, MacKay A, Whittall K, Kiehl K, Smith A, Hare R . Functional magnetic resonance imaging: the basics of blood-oxygen-level dependent (BOLD) imaging. Can Assoc Radiol J. 1998; 49(5):320-9. View

11.

Laking G, Price P . 18-Fluorodeoxyglucose positron emission tomography (FDG-PET) and the staging of early lung cancer. Thorax. 2001; 56 Suppl 2:ii38-44. PMC: 1765989. View

12.

Kim K, MacFall J, Payne M . Classification of white matter lesions on magnetic resonance imaging in elderly persons. Biol Psychiatry. 2008; 64(4):273-80. PMC: 2593803. DOI: 10.1016/j.biopsych.2008.03.024. View

13.

Sener R . Diffusion MRI: apparent diffusion coefficient (ADC) values in the normal brain and a classification of brain disorders based on ADC values. Comput Med Imaging Graph. 2001; 25(4):299-326. DOI: 10.1016/s0895-6111(00)00083-5. View

14.

Monroe T, Gore J, Bruehl S, Benningfield M, Dietrich M, Chen L . Sex differences in psychophysical and neurophysiological responses to pain in older adults: a cross-sectional study. Biol Sex Differ. 2015; 6:25. PMC: 4647695. DOI: 10.1186/s13293-015-0041-y. View

15.

Le Bihan D . Looking into the functional architecture of the brain with diffusion MRI. Nat Rev Neurosci. 2003; 4(6):469-80. DOI: 10.1038/nrn1119. View

16.

Paans A, van Waarde A, Elsinga P, Willemsen A, Vaalburg W . Positron emission tomography: the conceptual idea using a multidisciplinary approach. Methods. 2002; 27(3):195-207. DOI: 10.1016/s1046-2023(02)00075-0. View

17.

Brenner D, Hall E . Computed tomography--an increasing source of radiation exposure. N Engl J Med. 2007; 357(22):2277-84. DOI: 10.1056/NEJMra072149. View

18.

Monroe T, Gore J, Chen L, Mion L, Cowan R . Pain in people with Alzheimer disease: potential applications for psychophysical and neurophysiological research. J Geriatr Psychiatry Neurol. 2013; 25(4):240-55. PMC: 4455539. DOI: 10.1177/0891988712466457. View

19.

Cardis E, Vrijheid M, Blettner M, Gilbert E, Hakama M, Hill C . The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: estimates of radiation-related cancer risks. Radiat Res. 2007; 167(4):396-416. DOI: 10.1667/RR0553.1. View

20.

Lusic H, Grinstaff M . X-ray-computed tomography contrast agents. Chem Rev. 2012; 113(3):1641-66. PMC: 3878741. DOI: 10.1021/cr200358s. View