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An Evaluation Of Antibiotics Prescribing Patterns In The Emergency Department Of A Tertiary Care Hospital In Saudi Arabia

Abstract

Background: Antibiotic prescriptions at emergency departments (ED) could be a primary contributing factor to the overuse of antimicrobial agents and subsequently antimicrobial resistance. The aim of this study was to describe the pattern of antibiotic prescriptions at an emergency department of a tertiary care hospital in Saudi Arabia.

Methods: A cross-sectional study, based on a review of antibiotic prescriptions was conducted. All cases who visited the emergency department over a three-month period with a complaint of infection were analyzed in terms of patient characteristics (age, sex, infection type, and number of visits) and prescription characteristics (antibiotic category, spectrum, course and costs). The World Health Organization and International Network of Rational Use of Drugs prescribing indicators were presented. Descriptive and analytic statistics were applied.

Results: A total of 36,069 ED visits were recorded during the study period, of which 45,770 drug prescriptions were prescribed, including 6,354 antibiotics. The average number of drugs per encounter was 1.26, while the percentage of encounters with a prescribed antibiotic was 17.6%. Among antibiotic prescriptions, the percentage of encounters with injection antibiotics was 15.2%. Almost 77% of antibiotics were prescribed by their generic names, and the percentage of antibiotics prescribed from the essential list was 100%.

Conclusion: The average number of drugs per encounter in general and antibiotics per encounter in specific at this setting was lower than the standard value. However, the percentage of antibiotics prescribed by its generic name was less than optimal.

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References
1.
Atif M, Azeem M, Sarwar M, Shahid S, Javaid S, Ikram H . WHO/INRUD prescribing indicators and prescribing trends of antibiotics in the Accident and Emergency Department of Bahawal Victoria Hospital, Pakistan. Springerplus. 2016; 5(1):1928. PMC: 5099312. DOI: 10.1186/s40064-016-3615-1. View

2.
Laxminarayan R, Duse A, Wattal C, Zaidi A, Wertheim H, Sumpradit N . Antibiotic resistance-the need for global solutions. Lancet Infect Dis. 2013; 13(12):1057-98. DOI: 10.1016/S1473-3099(13)70318-9. View

3.
Shapiro D, Hicks L, Pavia A, Hersh A . Antibiotic prescribing for adults in ambulatory care in the USA, 2007-09. J Antimicrob Chemother. 2013; 69(1):234-40. DOI: 10.1093/jac/dkt301. View

4.
Dellit T, Owens R, McGowan Jr J, Gerding D, Weinstein R, Burke J . Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis. 2006; 44(2):159-77. DOI: 10.1086/510393. View

5.
Alanazi M, Alqahtani F, Aleanizy F . An evaluation of E. coli in urinary tract infection in emergency department at KAMC in Riyadh, Saudi Arabia: retrospective study. Ann Clin Microbiol Antimicrob. 2018; 17(1):3. PMC: 5806437. DOI: 10.1186/s12941-018-0255-z. View