» Articles » PMID: 31791130

Roles of TRPV4 and Piezo Channels in Stretch-evoked Ca Response in Chondrocytes

Overview
Specialty Biology
Date 2019 Dec 4
PMID 31791130
Citations 72
Authors
Affiliations
Soon will be listed here.
Citing Articles

Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation.

Zhu Y, Meng X, Zhai Q, Xin L, Tan H, He X Genes Dis. 2025; 12(2):101434.

PMID: 39759122 PMC: 11697055. DOI: 10.1016/j.gendis.2024.101434.


Microfabrication Technologies for Nanoinvasive and High-Resolution Magnetic Neuromodulation.

Ge C, Masalehdan T, Shojaei Baghini M, Duran Toro V, Signorelli L, Thomson H Adv Sci (Weinh). 2024; 11(46):e2404254.

PMID: 39445520 PMC: 11633526. DOI: 10.1002/advs.202404254.


Mechanical stimulation promotes fibrochondrocyte proliferation by activating the TRPV4 signaling pathway during tendon-bone insertion healing: CCN2 plays an important regulatory role.

Bian X, Liu X, Zhou M, Tang H, Wang R, Ma L Burns Trauma. 2024; 12:tkae028.

PMID: 39429645 PMC: 11491146. DOI: 10.1093/burnst/tkae028.


Insufficient Mechanical Loading Downregulates Piezo1 in Chondrocytes and Impairs Fracture Healing Through ApoE-Induced Senescence.

Jia S, Liu W, Zhang M, Wang L, Ren C, Feng C Adv Sci (Weinh). 2024; 11(46):e2400502.

PMID: 39418070 PMC: 11633519. DOI: 10.1002/advs.202400502.


The role of mechanosensitive ion channel Piezo1 in knee osteoarthritis inflammation.

He D, Liu X, Yang W, Guan T, Wang G Channels (Austin). 2024; 18(1):2393088.

PMID: 39169878 PMC: 11346567. DOI: 10.1080/19336950.2024.2393088.


References
1.
Soattin L, Fiore M, Gavazzo P, Viti F, Facci P, Raiteri R . The biophysics of piezo1 and piezo2 mechanosensitive channels. Biophys Chem. 2015; 208:26-33. DOI: 10.1016/j.bpc.2015.06.013. View

2.
OConor C, Leddy H, Benefield H, Liedtke W, Guilak F . TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. Proc Natl Acad Sci U S A. 2014; 111(4):1316-21. PMC: 3910592. DOI: 10.1073/pnas.1319569111. View

3.
Moroni M, Servin-Vences M, Fleischer R, Sanchez-Carranza O, Lewin G . Voltage gating of mechanosensitive PIEZO channels. Nat Commun. 2018; 9(1):1096. PMC: 5854696. DOI: 10.1038/s41467-018-03502-7. View

4.
Lu J, Liu F, Liu D, Du H, Hao J, Yang X . Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats. Exp Biol Med (Maywood). 2016; 241(11):1237-49. PMC: 4950312. DOI: 10.1177/1535370216630180. View

5.
Mamenko M, Zaika O, Boukelmoune N, ONeil R, Pochynyuk O . Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron. Am J Physiol Renal Physiol. 2014; 308(4):F275-86. PMC: 4329491. DOI: 10.1152/ajprenal.00485.2014. View