Methotrexate-induced Hemothorax in a Woman with Low-risk Metastatic Gestational Trophoblastic Disease
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Abstract
•Patients with invasive mole have a risk of bleeding to fragility and vascularity of the tumor.•Some patients may experience life-threatening bleeding.•Chemotherapy of patients with invasive/metastatic mole may induce bleeding.•In our patient with pulmonary metastatic mole, massive hemorrhage occurred 2 h after the first dose of MTX.•Our patient was successfully treated with partial resection of the bleeding tumor and additional 2 cycles of MTX.
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PMID: 33455574 PMC: 7812724. DOI: 10.1186/s13256-020-02630-3.
References
1.
Choi S, Goo J, Kim H, Im J
. Pulmonary arteriovenous fistulas developed after chemotherapy of metastatic choriocarcinoma. AJR Am J Roentgenol. 2003; 181(6):1544-6.
DOI: 10.2214/ajr.181.6.1811544.
View
2.
EVANS T, Zuidema G, Anderson D, Bookstein J
. Metastatic chorioadenoma destruens with intestinal hemorrhage. Obstet Gynecol. 1965; 26(4):570-4.
View
3.
Lurain J, Brewer J, TOROK E, Halpern B
. Gestational trophoblastic disease: treatment results at the Brewer Trophoblastic Disease Center. Obstet Gynecol. 1982; 60(3):354-60.
View
4.
Method M, Hirschfield M, Everette H
. Angiographic-guided embolization of metastatic invasive mole. Gynecol Oncol. 1996; 61(3):442-5.
DOI: 10.1006/gyno.1996.0171.
View
5.
McDonald-Burrows Z, Davies R, Goode E, Clarke C, Jackson J, Seckl M
. Haemoptysis from a pulmonary arteriovenous malformation in a post molar pregnancy gestational trophoblast tumour patient managed by radiological embolisation: a case report. J Med Case Rep. 2014; 8:117.
PMC: 4066323.
DOI: 10.1186/1752-1947-8-117.
View