Highly Efficient Tunable Picosecond Deep Ultraviolet Laser System for Raman Spectroscopy

Overview

Journal Opt Lett

Specialty Ophthalmology

Date 2019 Nov 28

PMID 31774773

Citations 1

Authors

Anton D Shutov

Georgi V Petrov

Da-Wei Wang

Marlan O Scully

Vladislav V Yakovlev

Affiliations

Soon will be listed here.

Abstract

We present a narrowband laser system tunable from 219 to 236 nm for deep ultraviolet (DUV) Raman spectroscopy. The demonstrated laser system produces 6.7 ps nearly transform-limited pulses with energy up to 0.36 µJ at 100 kHz repetition rate. The system consists of a two-stage optical parametric amplifier (OPA) of a narrowband continuous wave diode laser and subsequent frequency conversion to the DUV radiation. We achieve more than 300 mW in the signal wave using ${{\rm LiB}_3}{{\rm O}_5}$LiBO (LBO) and ${{\rm BaB}_2}{{\rm O}_4}$BaBO (BBO) crystals, with the total 2.7 W pump after the two-stage OPA. We reach 12% conversion efficiency of the OPA signal wave into the DUV radiation using type-I phase matching in the BBO crystal. Finally, we demonstrate the applicability of the system for DUV Raman spectroscopy by collecting a high dynamic range, high spectral resolution spontaneous Raman spectrum of air.

Citing Articles

Biomedical optics applications of advanced lasers and nonlinear optics.

Marble C, Yakovlev V J Biomed Opt. 2020; 25(4):1-9.

PMID: 32329266 PMC: 7177183. DOI: 10.1117/1.JBO.25.4.040902.

References

Nelson W, Dasari R, Feld M, Sperry J . Intensities of calcium dipicolinate and Bacillus subtilis spore Raman spectra excited with 244 nm light. Appl Spectrosc. 2004; 58(12):1408-12. DOI: 10.1366/0003702042641290. View

Lednev I, Ermolenkov V, He W, Xu M . Deep-UV Raman spectrometer tunable between 193 and 205 nm for structural characterization of proteins. Anal Bioanal Chem. 2004; 381(2):431-7. DOI: 10.1007/s00216-004-2991-5. View

Thompson J, Hokr B, Kim W, Ballmann C, Applegate B, Jo J . Enhanced coupling of light into a turbid medium through microscopic interface engineering. Proc Natl Acad Sci U S A. 2017; 114(30):7941-7946. PMC: 5544321. DOI: 10.1073/pnas.1705612114. View

Bixler J, Cone M, Hokr B, Mason J, Figueroa E, Fry E . Ultrasensitive detection of waste products in water using fluorescence emission cavity-enhanced spectroscopy. Proc Natl Acad Sci U S A. 2014; 111(20):7208-11. PMC: 4034222. DOI: 10.1073/pnas.1403175111. View

Asher S, Johnson C . Raman spectroscopy of a coal liquid shows that fluorescence interference is minimized with ultraviolet excitation. Science. 1984; 225(4659):311-3. DOI: 10.1126/science.6740313. View

Ballmann C, Petrov G, Yakovlev V . Simple approach to high-fidelity tunable narrow-band pulse generation. Opt Lett. 2017; 42(1):89-92. DOI: 10.1364/OL.42.000089. View

Freudiger C, Min W, Saar B, Lu S, Holtom G, He C . Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science. 2008; 322(5909):1857-61. PMC: 3576036. DOI: 10.1126/science.1165758. View

Sun Z, Ghotbi M, Zadeh M . Widely tunable picosecond optical parametric generation and amplification in BiB(3)O(6). Opt Express. 2009; 15(7):4139-48. DOI: 10.1364/oe.15.004139. View

Kneipp K, Kneipp H, Itzkan I, Dasari R, Feld M . Ultrasensitive chemical analysis by Raman spectroscopy. Chem Rev. 2001; 99(10):2957-76. DOI: 10.1021/cr980133r. View

10.

Petrov G, Arora R, Yakovlev V, Wang X, Sokolov A, Scully M . Comparison of coherent and spontaneous Raman microspectroscopies for noninvasive detection of single bacterial endospores. Proc Natl Acad Sci U S A. 2007; 104(19):7776-9. PMC: 1876523. DOI: 10.1073/pnas.0702107104. View

11.

Bykov S, Lednev I, Ianoul A, Mikhonin A, Munro C, Asher S . Steady-state and transient ultraviolet resonance Raman spectrometer for the 193-270 nm spectral region. Appl Spectrosc. 2006; 59(12):1541-52. DOI: 10.1366/000370205775142511. View

12.

Oladepo S, Xiong K, Hong Z, Asher S, Handen J, Lednev I . UV resonance Raman investigations of peptide and protein structure and dynamics. Chem Rev. 2012; 112(5):2604-28. PMC: 3349015. DOI: 10.1021/cr200198a. View

13.

Case A, Tan D, Stickel R, Mastromarino J . Narrow-linewidth, tunable ultraviolet, Ti:sapphire laser for environmental sensing. Appl Opt. 2006; 45(10):2306-9. DOI: 10.1364/ao.45.002306. View

14.

Balakrishnan G, Hu Y, Nielsen S, Spiro T . Tunable kHz deep ultraviolet (193-210 nm) laser for Raman application. Appl Spectrosc. 2005; 59(6):776-81. DOI: 10.1366/0003702054280702. View