Extracellular Phospholipase A2: Causative Agent in Circulatory Collapse of Septic Shock?

Overview

Journal Agents Actions

Specialty Pharmacology

Date 1988 Jul 1

PMID 3177094

Citations 10

Authors

P Vadas

W Pruzanski

E Stefanski

Affiliations

Soon will be listed here.

Citing Articles

Tenidap sodium inhibits secretory non-pancreatic phospholipase A(2) synthesis by foetal rat calvarial osteoblasts.

Pruzanski W, Kennedy B, Bosch H, Stefanski E, Wloch M, Vadas P Mediators Inflamm. 1995; 4(1):67-70.

PMID: 18475619 PMC: 2365603. DOI: 10.1155/S0962935195000123.

Phospholipase A(2) Activity in Gingival Crevicular Fluid from Patients with Periodontal Disease: A possible Marker of Disease Activity.

Ishida H, Shinohara H, Nagata T, Nishikawa S, Wakano Y Mediators Inflamm. 1994; 3(1):17-21.

PMID: 18472918 PMC: 2367015. DOI: 10.1155/S0962935194000037.

Effect of a series of 1-alkyl ether lipids on inhibition of phospholipase A2 activity and PAF responses.

Kohler C, Carroll M, Tarrant E, Torley L, Wissner A Inflammation. 1993; 17(3):245-61.

PMID: 8330926 DOI: 10.1007/BF00918988.

Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion.

Hatch G, Vance D, Wilton D Biochem J. 1993; 293 ( Pt 1):143-50.

PMID: 8328956 PMC: 1134332. DOI: 10.1042/bj2930143.

Selective inhibition of group II phospholipase A2 by quercetin.

Lindahl M, Tagesson C Inflammation. 1993; 17(5):573-82.

PMID: 8225564 DOI: 10.1007/BF00914195.

References

Vadas P, Hay J . Involvement of circulating phospholipase A2 in the pathogenesis of the hemodynamic changes in endotoxin shock. Can J Physiol Pharmacol. 1983; 61(6):561-6. DOI: 10.1139/y83-086. View

Pruzanski W, Keystone E, Sternby B, Bombardier C, Snow K, Vadas P . Serum phospholipase A2 correlates with disease activity in rheumatoid arthritis. J Rheumatol. 1988; 15(9):1351-5. View

Kreger B, Craven D, Carling P, McCabe W . Gram-negative bacteremia. III. Reassessment of etiology, epidemiology and ecology in 612 patients. Am J Med. 1980; 68(3):332-43. DOI: 10.1016/0002-9343(80)90101-1. View

Habermann E . [Pharmacology of phospholipase A]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1957; 230(6):538-46. View

Hirata F, Schiffmann E, Venkatasubramanian K, Salomon D, Axelrod J . A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids. Proc Natl Acad Sci U S A. 1980; 77(5):2533-6. PMC: 349435. DOI: 10.1073/pnas.77.5.2533. View

Chang J, Gilman S, Lewis A . Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action. J Immunol. 1986; 136(4):1283-7. View

Vadas P, Hay J . Secretion of a hyperemia-inducing moiety by mitogen or glycogen stimulated mononuclear inflammatory cells of sheep and rabbit. Int Arch Allergy Appl Immunol. 1980; 62(2):142-51. DOI: 10.1159/000232506. View

Lefer A . Eicosanoids as mediators of ischemia and shock. Fed Proc. 1985; 44(2):275-80. View

Vadas P . Elevated plasma phospholipase A2 levels: correlation with the hemodynamic and pulmonary changes in gram-negative septic shock. J Lab Clin Med. 1984; 104(6):873-81. View

10.

Wilson M, Brackett D . Release of vasoactive hormones and circulatory changes in shock. Circ Shock. 1983; 11(3):225-34. View

11.

Sprung C, Caralis P, Marcial E, Pierce M, Gelbard M, LONG W . The effects of high-dose corticosteroids in patients with septic shock. A prospective, controlled study. N Engl J Med. 1984; 311(18):1137-43. DOI: 10.1056/NEJM198411013111801. View

12.

Vadas P, Pruzanski W, Stefanski E, Sternby B, Mustard R, Bohnen J . Pathogenesis of hypotension in septic shock: correlation of circulating phospholipase A2 levels with circulatory collapse. Crit Care Med. 1988; 16(1):1-7. DOI: 10.1097/00003246-198801000-00001. View

13.

Shakir K, OBrian J, Gartner S . Enhanced phospholipase A2 activity in rat plasma, liver, and intestinal mucosa following endotoxin treatment: a possible explanation for the protective effect of indomethacin in endotoxic shock. Metabolism. 1985; 34(2):176-82. DOI: 10.1016/0026-0495(85)90129-5. View

14.

Zimmerman J, Dietrich K . Current perspectives on septic shock. Pediatr Clin North Am. 1987; 34(1):131-63. DOI: 10.1016/s0031-3955(16)36186-7. View

15.

Schmidt D, Hoffmann G . Activity of phospholipase A compared in serum of patients with pancreatic and nonpancreatic diseases. Clin Chem. 1987; 33(4):594-6. View

16.

Flynn J, Henry J, Perkowski S . Phospholipase A2 stimulated release of prostanoids from the isolated, perfused rabbit liver: implications in regional cellular injury. Can J Physiol Pharmacol. 1981; 59(12):1268-73. DOI: 10.1139/y81-198. View

17.

Vadas P, Wasi S, Movat H, Hay J . Extracellular phospholipase A2 mediates inflammatory hyperaemia. Nature. 1981; 293(5833):583-5. DOI: 10.1038/293583a0. View

18.

URBASCHEK B, Urbaschek R . The inflammatory response to endotoxins. Bibl Anat. 1979; (17):74-104. View

19.

Vadas P, Pruzanski W, Stefanski E, Ruse J, Farewell V, McLaughlin J . Concordance of endogenous cortisol and phospholipase A2 levels in gram-negative septic shock: a prospective study. J Lab Clin Med. 1988; 111(5):584-90. View

20.

Hallman M, Spragg R, Harrell J, Moser K, Gluck L . Evidence of lung surfactant abnormality in respiratory failure. Study of bronchoalveolar lavage phospholipids, surface activity, phospholipase activity, and plasma myoinositol. J Clin Invest. 1982; 70(3):673-83. PMC: 370271. DOI: 10.1172/jci110662. View