Roles of Mast Cells in Rheumatoid Arthritis

Overview

Journal Korean J Intern Med

Specialty General Medicine

Date 2019 Nov 15

PMID 31722515

Citations 15

Authors

Hong Ki Min

Kyoung-Woon Kim

Sang-Heon Lee

Hae-Rim Kim

Affiliations

Soon will be listed here.

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthritis, and the complex interaction and activation of innate and adaptive immune cells are involved in RA pathogenesis. Mast cells (MCs) are one of the tissue-resident innate immune cells, and they contribute to RA pathogenesis. In the present review, the evidence of the pathologic role of MC in RA is discussed based on human and animal data. In addition, the potential role of MC in RA pathogenesis and the research area that should be focused on in the future are suggested.

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