Hypertensive Urgencies and Emergencies: Misconceptions and Pitfalls

Overview

Journal Eur J Intern Med

Specialty General Medicine

Date 2019 Nov 11

PMID 31706707

Citations 3

Authors

Fabio Angeli

Gianpaolo Reboldi

Paolo Verdecchia

Affiliations

Soon will be listed here.

Citing Articles

Hypertensive urgencies during the first wave of the COVID-19 pandemic in a tertiary hospital setting: a U-shaped alarming curve.

Leontsinis I, Papademetriou V, Chrysohoou C, Kariori M, Dalakouras I, Tolis P Arch Med Sci. 2022; 18(4):982-990.

PMID: 35832718 PMC: 9266735. DOI: 10.5114/aoms/141243.

The Natural-Mineral-Based Novel Nanomaterial IFMC Increases Intravascular Nitric Oxide without Its Intake: Implications for COVID-19 and beyond.

Akiyama T, Hirata T, Fujimoto T, Hatakeyama S, Yamazaki R, Nomura T Nanomaterials (Basel). 2020; 10(9).

PMID: 32872395 PMC: 7559745. DOI: 10.3390/nano10091699.

Could Ergothioneine Aid in the Treatment of Coronavirus Patients?.

Cheah I, Halliwell B Antioxidants (Basel). 2020; 9(7).

PMID: 32646061 PMC: 7402156. DOI: 10.3390/antiox9070595.

References

Booth C, Matukas L, Tomlinson G, Rachlis A, Rose D, Dwosh H . Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA. 2003; 289(21):2801-9. DOI: 10.1001/jama.289.21.JOC30885. View

Mehta P, Griendling K . Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol. 2006; 292(1):C82-97. DOI: 10.1152/ajpcell.00287.2006. View

Fraga-Silva R, Costa-Fraga F, De Sousa F, Alenina N, Bader M, Sinisterra R . An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect. Clinics (Sao Paulo). 2011; 66(5):837-41. PMC: 3109384. DOI: 10.1590/s1807-59322011000500021. View

Li W, Moore M, Vasilieva N, Sui J, Wong S, Berne M . Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003; 426(6965):450-4. PMC: 7095016. DOI: 10.1038/nature02145. View

Tang N, Li D, Wang X, Sun Z . Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020; 18(4):844-847. PMC: 7166509. DOI: 10.1111/jth.14768. View

Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu P . Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction. Circ Heart Fail. 2009; 2(5):446-55. DOI: 10.1161/CIRCHEARTFAILURE.108.840124. View

Glowacka I, Bertram S, Muller M, Allen P, Soilleux E, Pfefferle S . Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response. J Virol. 2011; 85(9):4122-34. PMC: 3126222. DOI: 10.1128/JVI.02232-10. View

Hamming I, Timens W, Bulthuis M, Lely A, Navis G, van Goor H . Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004; 203(2):631-7. PMC: 7167720. DOI: 10.1002/path.1570. View

Hung Y, Hsieh W, Hsieh J, Liu F, Tsai C, Lu L . Alternative Roles of STAT3 and MAPK Signaling Pathways in the MMPs Activation and Progression of Lung Injury Induced by Cigarette Smoke Exposure in ACE2 Knockout Mice. Int J Biol Sci. 2016; 12(4):454-65. PMC: 4807164. DOI: 10.7150/ijbs.13379. View

10.

Xu J, Sriramula S, Xia H, Moreno-Walton L, Culicchia F, Domenig O . Clinical Relevance and Role of Neuronal AT Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic Hypertension. Circ Res. 2017; 121(1):43-55. PMC: 5507353. DOI: 10.1161/CIRCRESAHA.116.310509. View

11.

Gembardt F, Sterner-Kock A, Imboden H, Spalteholz M, Reibitz F, Schultheiss H . Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents. Peptides. 2005; 26(7):1270-7. PMC: 7115528. DOI: 10.1016/j.peptides.2005.01.009. View

12.

Chen Q, Yang Y, Huang Y, Pan C, Liu L, Qiu H . Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury. J Surg Res. 2013; 185(2):740-7. DOI: 10.1016/j.jss.2013.06.052. View

13.

Pai W, Lo W, Hsu T, Peng C, Wang H . Angiotensin-(1-7) Inhibits Thrombin-Induced Endothelial Phenotypic Changes and Reactive Oxygen Species Production via NADPH Oxidase 5 Downregulation. Front Physiol. 2018; 8:994. PMC: 5770656. DOI: 10.3389/fphys.2017.00994. View

14.

Mancia G . Highlights of the January issue. J Hypertens. 2019; 38(1):1-2. DOI: 10.1097/HJH.0000000000002301. View

15.

Magalhaes G, Rodrigues-Machado M, Motta-Santos D, Silva A, Caliari M, Prata L . Angiotensin-(1-7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation. Br J Pharmacol. 2015; 172(9):2330-42. PMC: 4403097. DOI: 10.1111/bph.13057. View

16.

Wang W, Patel V, Parajuli N, Fan D, Basu R, Wang Z . Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease. J Mol Med (Berl). 2014; 92(8):847-58. DOI: 10.1007/s00109-014-1149-y. View

17.

Trask A, Averill D, Ganten D, Chappell M, Ferrario C . Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats. Am J Physiol Heart Circ Physiol. 2007; 292(6):H3019-24. DOI: 10.1152/ajpheart.01198.2006. View

18.

Wysocki J, Ye M, Rodriguez E, Gonzalez-Pacheco F, Barrios C, Evora K . Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension. Hypertension. 2009; 55(1):90-8. PMC: 2827767. DOI: 10.1161/HYPERTENSIONAHA.109.138420. View

19.

Liang B, Wang X, Zhang N, Yang H, Bai R, Liu M . Angiotensin-(1-7) Attenuates Angiotensin II-Induced ICAM-1, VCAM-1, and MCP-1 Expression via the MAS Receptor Through Suppression of P38 and NF-κB Pathways in HUVECs. Cell Physiol Biochem. 2015; 35(6):2472-82. DOI: 10.1159/000374047. View

20.

Santos R, Sampaio W, Alzamora A, Motta-Santos D, Alenina N, Bader M . The ACE2/Angiotensin-(1-7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1-7). Physiol Rev. 2018; 98(1):505-553. PMC: 7203574. DOI: 10.1152/physrev.00023.2016. View