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Database Resources of the National Genomics Data Center in 2020

Overview
Specialty Biochemistry
Date 2019 Nov 9
PMID 31702008
Citations 123
Affiliations
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Abstract

The National Genomics Data Center (NGDC) provides a suite of database resources to support worldwide research activities in both academia and industry. With the rapid advancements in higher-throughput and lower-cost sequencing technologies and accordingly the huge volume of multi-omics data generated at exponential scales and rates, NGDC is continually expanding, updating and enriching its core database resources through big data integration and value-added curation. In the past year, efforts for update have been mainly devoted to BioProject, BioSample, GSA, GWH, GVM, NONCODE, LncBook, EWAS Atlas and IC4R. Newly released resources include three human genome databases (PGG.SNV, PGG.Han and CGVD), eLMSG, EWAS Data Hub, GWAS Atlas, iSheep and PADS Arsenal. In addition, four web services, namely, eGPS Cloud, BIG Search, BIG Submission and BIG SSO, have been significantly improved and enhanced. All of these resources along with their services are publicly accessible at https://bigd.big.ac.cn.

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References
1.
Zhang C, Gao Y, Ning Z, Lu Y, Zhang X, Liu J . PGG.SNV: understanding the evolutionary and medical implications of human single nucleotide variations in diverse populations. Genome Biol. 2019; 20(1):215. PMC: 6805450. DOI: 10.1186/s13059-019-1838-5. View

2.
Du Z, Ma L, Qu H, Chen W, Zhang B, Lu X . Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome. Genomics Proteomics Bioinformatics. 2019; 17(3):229-247. PMC: 6818495. DOI: 10.1016/j.gpb.2019.07.002. View

3.
Niu G, Zou D, Li M, Zhang Y, Sang J, Xia L . Editome Disease Knowledgebase (EDK): a curated knowledgebase of editome-disease associations in human. Nucleic Acids Res. 2018; 47(D1):D78-D83. PMC: 6323952. DOI: 10.1093/nar/gky958. View

4.
. The BIG Data Center: from deposition to integration to translation. Nucleic Acids Res. 2016; 45(D1):D18-D24. PMC: 5210546. DOI: 10.1093/nar/gkw1060. View

5.
Ma L, Cao J, Liu L, Li Z, Shireen H, Pervaiz N . Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook. Curr Protoc Bioinformatics. 2019; 67(1):e82. DOI: 10.1002/cpbi.82. View