Genotyping and Zoonotic Potential of in Pigs in Xinjiang, China

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2019 Nov 8

PMID 31695688

Citations 14

Authors

Dong-Fang Li

Ying Zhang

Yu-Xi Jiang

Jin-Ming Xing

Da-Yong Tao

Ai-Yun Zhao

Zhao-Hui Cui

Bo Jing

Meng Qi

Long-Xian Zhang

Affiliations

Soon will be listed here.

Abstract

is an obligate intracellular fungus, infecting various invertebrate and vertebrate hosts, it is common in humans and causes diarrhea in the immunocompromised. In the present study, 801 fecal specimens were collected from pigs on seven large-scale pig farms in Xinjiang, China. Nested polymerase chain reaction (PCR) amplification of the internal transcribed spacer (ITS) gene showed that the overall i infection rate was 48.6% (389/801). The infection rates differed significantly among the collection sites (20.0-73.0%) (χ = 75.720, = 6, < 0.01). Post-weaned pigs had the highest infection rate (77.2%, 217/281), followed by fattening pigs (67.4%, 87/129) and pre-weaned suckling pigs (35.5%, 60/169). Adult pigs had the lowest infection rate (11.3%, 25/222). The infection rates also differed significantly among age groups (χ = 246.015, = 3, < 0.01). Fifteen genotypes were identified, including 13 known genotypes (CHC, CS-1, CS-4, CS-7, CS-9, D, EbpA, EbpC, EbpD, H, PigEb4, PigEBITS5, and WildBoar8) and two novel genotypes (XJP-II and XJP-III). Among them, six genotypes (CS-4, D, EbpA, EbpC, H, and PigEBITS5) have been reported in humans. Phylogenetic analysis showed that all the genotypes belonged to Group 1 of . These findings suggest that pigs may play an important role in transmitting infections to humans.

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