Biocide Potentiation Using Cinnamic Phytochemicals and Derivatives

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2019 Nov 2

PMID 31671687

Citations 8

Authors

Joana F Malheiro

Jean-Yves Maillard

Fernanda Borges

Manuel Simoes

Affiliations

Soon will be listed here.

Abstract

Surface disinfection is of utmost importance in the prevention of bacterial infections. This study aims to assess the ability of ten phytochemicals and related derivatives as potentiators of two commonly used biocides-cetyltrimethylammonium bromide (CTAB) and lactic acid (LA). LA in combination with cinnamic, hydrocinnamic, α-methylcinnamic, and α-fluorocinnamic acids had a factional inhibitory concentration index (FICI) ≤ 1 for and . Several phytochemicals/derivatives in combination with biocides improved the biocidal efficacy against early sessile bacteria. The most effective combination was LA with allyl cinnamate (2.98 ± 0.76 log CFU.cm reduction) against . The combination with CTAB was successful for most phytochemicals/derivatives with a maximum bactericidal efficacy against sessile when combined with allyl cinnamate (2.20 ± 0.07 log CFU.cm reduction) and for when combined with α-methylcinnamic acid (1.68 ± 0.30 log CFU.cm reduction). This study highlights the potential of phytochemicals and their derivatives to be used in biocide formulations.

Citing Articles

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