Future Directions for Meningitis Surveillance and Vaccine Evaluation in the Meningitis Belt of Sub-Saharan Africa

Overview

Journal J Infect Dis

Publisher Oxford University Press

Specialty Infectious Diseases

Date 2019 Nov 1

PMID 31671452

Citations 15

Authors

Ryan T Novak

Olivier Ronveaux

Andre F Bita

Honore Flavien Ake

Fernanda C Lessa

Xin Wang

Ado M Bwaka

LeAnne M Fox

Affiliations

Soon will be listed here.

Abstract

In sub-Saharan Africa, bacterial meningitis remains a significant public health problem, especially in the countries of the meningitis belt, where Neisseria meningitidis serogroup A historically caused large-scale epidemics. In 2014, MenAfriNet was established as a consortium of partners supporting strategic implementation of case-based meningitis surveillance to monitor meningitis epidemiology and impact of meningococcal serogroup A conjugate vaccine (MACV). MenAfriNet improved data quality through use of standardized tools, procedures, and laboratory diagnostics. MenAfriNet surveillance and study data provided evidence of ongoing MACV impact, characterized the burden of non-serogroup A meningococcal disease (including the emergence of a new epidemic clone of serogroup C), and documented the impact of pneumococcal conjugate vaccine. New vaccines and schedules have been proposed for future implementation to address the remaining burden of meningitis. To support the goals of "Defeating Meningitis by 2030," MenAfriNet will continue to strengthen surveillance and support research and modeling to monitor the impact of these programs on meningitis burden in sub-Saharan Africa.

Citing Articles

Determining the bacterial and viral meningitis trend in Iraq from 2007 till 2023 using joinpoint regression.

Khaleel H, Alhilfi R, Rawaf S, Atwan Z, Al-Alwany A, Raheem M Heliyon. 2024; 10(9):e30088.

PMID: 38707473 PMC: 11066402. DOI: 10.1016/j.heliyon.2024.e30088.

Epidemiology and antimicrobial resistance patterns of bacterial meningitis among hospitalized patients at a tertiary care hospital in Saudi Arabia: a six-year retrospective study.

Alhazmi A, Alameer K, Abuageelah B, Gharawi A, Hakami E, Zogel T Eur J Clin Microbiol Infect Dis. 2024; 43(7):1383-1392.

PMID: 38683272 DOI: 10.1007/s10096-024-04835-6.

Meningitis in Niger Republic amidst COVID-19: current issues and novel recommendations.

Oduoye M, Akanbi-Hakeem H, Muzammil M, Arama U, Abbasi H, Farhan K Ann Med Surg (Lond). 2024; 86(1):345-352.

PMID: 38222679 PMC: 10783331. DOI: 10.1097/MS9.0000000000001511.

Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Lancet Neurol. 2023; 22(8):685-711.

PMID: 37479374 PMC: 10356620. DOI: 10.1016/S1474-4422(23)00195-3.

The Epidemiology of Meningococcal Disease and Carriage, Genotypic Characteristics and Antibiotic Resistance of Isolates in Zhejiang Province, China, 2011-2021.

Zhang Y, Deng X, Jiang Y, Zhang J, Zhan L, Mei L Front Microbiol. 2022; 12:801196.

PMID: 35140696 PMC: 8819144. DOI: 10.3389/fmicb.2021.801196.

References

Bozio C, Abdul-Karim A, Abenyeri J, Abubakari B, Ofosu W, Zoya J . Continued occurrence of serotype 1 pneumococcal meningitis in two regions located in the meningitis belt in Ghana five years after introduction of 13-valent pneumococcal conjugate vaccine. PLoS One. 2018; 13(9):e0203205. PMC: 6128537. DOI: 10.1371/journal.pone.0203205. View

Patel J, George J, Vuong J, Potts C, Bozio C, Clark T . Rapid Laboratory Identification of Neisseria meningitidis Serogroup C as the Cause of an Outbreak - Liberia, 2017. MMWR Morb Mortal Wkly Rep. 2017; 66(42):1144-1147. PMC: 5689101. DOI: 10.15585/mmwr.mm6642a5. View

Coldiron M, Toure O, Frank T, Bouygues N, Grais R . Outbreak of Pneumococcal Meningitis, Paoua Subprefecture, Central African Republic, 2016-2017. Emerg Infect Dis. 2018; 24(9):1720-1722. PMC: 6106441. DOI: 10.3201/eid2409.171058. View

. Meningococcal A conjugate vaccine: updated guidance, February 2015. Wkly Epidemiol Rec. 2015; 90(8):57-62. View

Yaro S, Njanpop Lafourcade B, Ouangraoua S, Ouoba A, Kpoda H, Findlow H . Antibody Persistence at the Population Level 5 Years After Mass Vaccination With Meningococcal Serogroup A Conjugate Vaccine (PsA-TT) in Burkina Faso: Need for a Booster Campaign?. Clin Infect Dis. 2018; 68(3):435-443. DOI: 10.1093/cid/ciy488. View

Novak R, Kambou J, Diomande F, Tarbangdo T, Ouedraogo-Traore R, Sangare L . Serogroup A meningococcal conjugate vaccination in Burkina Faso: analysis of national surveillance data. Lancet Infect Dis. 2012; 12(10):757-64. PMC: 4831863. DOI: 10.1016/S1473-3099(12)70168-8. View

Zoma R, Walldorf J, Tarbangdo F, Patel J, Diallo A, Nkwenkeu S . Evaluation of the Impact of Meningococcal Serogroup A Conjugate Vaccine Introduction on Second-Year-of-Life Vaccination Coverage in Burkina Faso. J Infect Dis. 2019; 220(220 Suppl 4):S233-S243. PMC: 10718265. DOI: 10.1093/infdis/jiz304. View

Sidikou F, Zaneidou M, Alkassoum I, Schwartz S, Issaka B, Obama R . Emergence of epidemic Neisseria meningitidis serogroup C in Niger, 2015: an analysis of national surveillance data. Lancet Infect Dis. 2016; 16(11):1288-1294. PMC: 5737706. DOI: 10.1016/S1473-3099(16)30253-5. View

Chow J, Uadiale K, Bestman A, Kamau C, Caugant D, Shehu A . Invasive Meningococcal Meningitis Serogroup C Outbreak in Northwest Nigeria, 2015 - Third Consecutive Outbreak of a New Strain. PLoS Curr. 2016; 8. PMC: 4958021. DOI: 10.1371/currents.outbreaks.06d10b6b4e690917d8b0a04268906143. View

10.

Chen W, Neuzil K, Boyce C, Pasetti M, Reymann M, Martellet L . Safety and immunogenicity of a pentavalent meningococcal conjugate vaccine containing serogroups A, C, Y, W, and X in healthy adults: a phase 1, single-centre, double-blind, randomised, controlled study. Lancet Infect Dis. 2018; 18(10):1088-1096. DOI: 10.1016/S1473-3099(18)30400-6. View

11.

Trotter C, Lingani C, Fernandez K, Cooper L, Bita A, Tevi-Benissan C . Impact of MenAfriVac in nine countries of the African meningitis belt, 2010-15: an analysis of surveillance data. Lancet Infect Dis. 2017; 17(8):867-872. DOI: 10.1016/S1473-3099(17)30301-8. View

12.

Alderson M, LaForce F, Sobanjo-Ter Meulen A, Hwang A, Preziosi M, Klugman K . Eliminating Meningococcal Epidemics From the African Meningitis Belt: The Case for Advanced Prevention and Control Using Next-Generation Meningococcal Conjugate Vaccines. J Infect Dis. 2019; 220(220 Suppl 4):S274-S278. PMC: 6822963. DOI: 10.1093/infdis/jiz297. View

13.

Retchless A, Fox L, Maiden M, Smith V, Harrison L, Glennie L . Toward a Global Genomic Epidemiology of Meningococcal Disease. J Infect Dis. 2019; 220(220 Suppl 4):S266-S273. DOI: 10.1093/infdis/jiz279. View

14.

Mbaeyi S, Lingani C, Diallo A, Bicaba B, Ouedraogo-Traore R, Acyl M . Improving Case-Based Meningitis Surveillance in 5 Countries in the Meningitis Belt of Sub-Saharan Africa, 2015-2017. J Infect Dis. 2019; 220(220 Suppl 4):S155-S164. DOI: 10.1093/infdis/jiz303. View

15.

Greenwood B . Pneumococcal meningitis epidemics in Africa. Clin Infect Dis. 2006; 43(6):701-3. DOI: 10.1086/506943. View

16.

. Preparedness for outbreaks of meningococcal meningitis due to Neisseria meningitidis serogroup C in Africa: recommendations from a WHO expert consultation. Wkly Epidemiol Rec. 2015; 90(47):633-6. View

17.

Daugla D, Gami J, Gamougam K, Naibei N, Mbainadji L, Narbe M . Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community study [corrected]. Lancet. 2013; 383(9911):40-47. PMC: 3898950. DOI: 10.1016/S0140-6736(13)61612-8. View

18.

Paye M, Gamougame K, Payamps S, Feagins A, Moto D, Moyengar R . Implementation of Case-Based Surveillance and Real-time Polymerase Chain Reaction to Monitor Bacterial Meningitis Pathogens in Chad. J Infect Dis. 2019; 220(220 Suppl 4):S182-S189. PMC: 6822964. DOI: 10.1093/infdis/jiz366. View

19.

Sanogo Y, Guindo I, Diarra S, Retchless A, Abdou M, Coulibaly S . A New Sequence Type of Neisseria meningitidis Serogroup C Associated With a 2016 Meningitis Outbreak in Mali. J Infect Dis. 2019; 220(220 Suppl 4):S190-S197. DOI: 10.1093/infdis/jiz272. View

20.

Fernandez K, Lingani C, Aderinola O, Goumbi K, Bicaba B, Edea Z . Meningococcal Meningitis Outbreaks in the African Meningitis Belt After Meningococcal Serogroup A Conjugate Vaccine Introduction, 2011-2017. J Infect Dis. 2019; 220(220 Suppl 4):S225-S232. PMC: 6822966. DOI: 10.1093/infdis/jiz355. View