» Articles » PMID: 31656869

Multimodal Analgesia in Pain Management After Spine Surgery

Overview
Journal J Spine Surg
Date 2019 Oct 29
PMID 31656869
Citations 19
Authors
Affiliations
Soon will be listed here.
Abstract

Multimodal analgesia (MMA) is the simultaneous use of multiple analgesic medications that work in a synergistic manner to provide pain control. In recent years, spine surgery has seen the growth of multimodal perioperative protocols for managing pain. Postoperative pain following spinal procedures is a common complaint, with persistent pain even after the immediate convalescent period leading to negative impacts on health. A multidisciplinary approach is essential in reducing postoperative morbidity and complication rates. This review demonstrates the efficacy in the combined use of opioid-alternative medications such as NSAIDs, gabapentinoids, local anesthetics, acetaminophen, and other neuromodulatory pharmacologic agents. Continued research will be essential in the optimization of the MMA protocol for treating patients who undergo spine procedures.

Citing Articles

Optimizing acute pain management in trauma care: the role, structure and core principles of acute trauma pain services.

Gupta K, Nalin S, Dogra S, Dar P Eur J Trauma Emerg Surg. 2025; 51(1):103.

PMID: 39945864 DOI: 10.1007/s00068-025-02778-x.


Association of Untreated Pre-surgical Depression With Pain and Outcomes After Spinal Surgery.

Shin J, Park Y, Park S, Ha J, Jung W, Kim H Global Spine J. 2024; :21925682241260642.

PMID: 38861501 PMC: 11571643. DOI: 10.1177/21925682241260642.


The impact of perioperative nonsteroidal anti-inflammatory drugs on the postoperative outcomes of spinal surgery: a meta-analysis of 23 randomized controlled trials.

Luo M, Yang G, Dai H, Shi F, Tang Z, Tan J Neurosurg Rev. 2024; 47(1):140.

PMID: 38578529 DOI: 10.1007/s10143-024-02371-7.


Postoperative pain and pain management following selective dorsal rhizotomy.

Adams I, Jayaweera R, Lewis J, Badawi N, Abdel-Latif M, Paget S BMJ Paediatr Open. 2024; 8(1).

PMID: 38490692 PMC: 10946356. DOI: 10.1136/bmjpo-2023-002381.


Does the Association Between Psychosocial Factors and Opioid Use After Elective Spine Surgery Differ by Sex in Older Adults?.

Aglio L, Mezzalira E, Corey S, Fields K, Hauser B, Susano M J Pain Res. 2023; 16:3477-3489.

PMID: 37873025 PMC: 10590566. DOI: 10.2147/JPR.S415714.


References
1.
Berger R, Jacobs J, Meneghini R, Della Valle C, Paprosky W, Rosenberg A . Rapid rehabilitation and recovery with minimally invasive total hip arthroplasty. Clin Orthop Relat Res. 2004; (429):239-47. DOI: 10.1097/01.blo.0000150127.80647.80. View

2.
Buvanendran A . Chronic postsurgical pain: are we closer to understanding the puzzle?. Anesth Analg. 2012; 115(2):231-2. DOI: 10.1213/ANE.0b013e318258b9f7. View

3.
Pugely A, Martin C, Gao Y, Mendoza-Lattes S . Causes and risk factors for 30-day unplanned readmissions after lumbar spine surgery. Spine (Phila Pa 1976). 2014; 39(9):761-8. DOI: 10.1097/BRS.0000000000000270. View

4.
Mathiesen O, Dahl B, Thomsen B, Kitter B, Sonne N, Dahl J . A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery. Eur Spine J. 2013; 22(9):2089-96. PMC: 3777071. DOI: 10.1007/s00586-013-2826-1. View

5.
Sivaganesan A, Chotai S, White-Dzuro G, McGirt M, Devin C . The effect of NSAIDs on spinal fusion: a cross-disciplinary review of biochemical, animal, and human studies. Eur Spine J. 2017; 26(11):2719-2728. DOI: 10.1007/s00586-017-5021-y. View