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Readmission Following Inpatient Stereotactic Radiosurgery for Brain Tumors

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Date 2019 Oct 24
PMID 31641547
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Abstract

Background: Stereotactic radiosurgery (SRS) is indicated for a spectrum of brain tumors and is often an outpatient procedure, though severe disease may precipitate inpatient treatment. Readmission following inpatient SRS for brain tumors is not well understood.

Objectives: To characterize rate, associative factors, and predictors of SRS readmission.

Methods: Retrospective analysis of inpatients treated with SRS for brain neoplasms was conducted (2010-2014 Nationwide Readmissions Database). Diagnoses upon readmission were characterized. Associations with 30-day readmission were identified using multivariate analyses.

Results: Of 2,553 patients undergoing SRS, 390 were readmitted (15.3%) within 30 days. Leading readmission diagnoses were infectious or embolic. Neurological readmissions of intracerebral hemorrhage (2.1%) and cerebral edema (1.5%) were rare. Malignant tumors (OR=1.60, p=0.007) and discharge to facility (OR=1.41, p=0.004) were associated with readmission.

Conclusion: Inpatients receiving SRS for brain tumors have a 15.3% 30-day readmission rate. Neurologic readmissions were rare, underscoring the neurological safety of SRS, even in sick inpatients.

References
1.
McClelland 3rd S, Jalai C, Ryu S, Passias P . Limitations of using population-based databases to assess trends in spinal stereotactic radiosurgery. J Radiosurg SBRT. 2018; 4(3):177-180. PMC: 5658800. View

2.
Shrieve D, Alexander 3rd E, Wen P, Fine H, Kooy H, Black P . Comparison of stereotactic radiosurgery and brachytherapy in the treatment of recurrent glioblastoma multiforme. Neurosurgery. 1995; 36(2):275-82; discussion 282-4. DOI: 10.1227/00006123-199502000-00006. View

3.
Lieu A, Hwang S, Howng S, Chai C . Brain tumors with hemorrhage. J Formos Med Assoc. 1999; 98(5):365-7. View

4.
Frischer J, Fraller A, Mallouhi A, Vogl U, Baier F, Ertl A . Evaluation of Dose-Staged Gamma Knife Radiosurgical Treatment Method for High-Risk Brain Metastases. World Neurosurg. 2016; 94:352-359. DOI: 10.1016/j.wneu.2016.07.038. View

5.
Milano M, Sharma M, Soltys S, Sahgal A, Usuki K, Saenz J . Radiation-Induced Edema After Single-Fraction or Multifraction Stereotactic Radiosurgery for Meningioma: A Critical Review. Int J Radiat Oncol Biol Phys. 2018; 101(2):344-357. DOI: 10.1016/j.ijrobp.2018.03.026. View