Giant Cell Tumor of Tendon Sheath in the Hand: Analysis of Risk Factors for Recurrence in 50 Cases

Overview

Journal BMC Musculoskelet Disord

Publisher Biomed Central

Specialties Orthopedics
Physiology

Date 2019 Oct 23

PMID 31638958

Citations 23

Authors

Hakan Ozben

Tamer Coskun

Affiliations

Soon will be listed here.

Abstract

Background: Giant cell tumor of the tendon sheath is the most common form of giant cell tumors and is the second most common soft tissue tumor of the hand region after ganglion cyst. Magnetic resonance imaging is the diagnostic tool of choice for both diagnosis and treatment planning. The current standard treatment of choice is simple excision. The main concern about the treatment is related to the high recurrence rates. Besides incomplete excision, there is no consensus concerning the effect of other risk factors on recurrence. The literature lacks detailed reports on surgical excision of these tumors with a standardized surgical treatment and an appropriate patient follow up. The aim of this study was to investigate the recurrence rate and the associated recurrence risk factors for giant cell tumor of tendon sheath of the hand following a standardized treatment.

Methods: The records of patients treated for giant cell tumor of tendon sheath of the hand treated by the same hand surgeon were evaluated retrospectively. The features obtained from preoperative magnetic resonance imaging, final physical examination, patients' age and sex, anatomical site of the tumor, relationship of the tumor with bone, joint or neurovascular structures, bone invasion, recurrence after surgery and complications like skin necrosis, digital neuropathy or limitation in range of motion were documented. Chi-square test was used to compare categorical variables.

Results: Fifty patient were included in the study. The average follow-up time was 84 months. Three recurrences (6%) were recorded. The only significant risk factor for the recurrence was tumor adjacency to the interphalangeal joints of the fingers other than thumb. No major or minor complications were encountered in the postoperative period.

Conclusion: With adequate surgical exposure and meticulous dissection provided by the magnification loupes, we were able demonstrate one of the lowest recurrence rates in the literature. Well-designed studies combining the recurrence rates of several hand surgery centers implementing a standardized treatment are needed to better demonstrate the associated risk factors for recurrence.

Citing Articles

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Giant Cell Tumor of the Synovial Pod of the Third Toe on the Right Foot: Report of a Case.

Grimaldi-Valencia C, Celis-Ochoa A, Ramirez-Garcia J, Flores-Vargas G, Padilla-Raygoza N Clin Med Insights Case Rep. 2024; 17:11795476241266100.

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A Giant Cell Tumor of the Tendon Sheath of the Foot: A Rare Presentation.

Inamdar A, Gattani R, Shinde R Cureus. 2024; 16(6):e63276.

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Multiple extraarticular giant cell tumors.

Yousefian F, Cortes M, Kahn B, Goodman M, Kounalakis N JAAD Case Rep. 2024; 49:17-19.

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Giant Cell Tumor of the Tendon Sheath of the Hand: Analysis of Factors Impacting Recurrence.

Kolisetty P, Ali S, Ahmad I, Sudhy I, Prakash O, Kishore Y Indian J Plast Surg. 2024; 57(2):123-128.

PMID: 38774731 PMC: 11105819. DOI: 10.1055/s-0044-1779657.

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