Full Genome Sequence Analysis of a 1-7-4-like PRRSV Strain in Fujian Province, China

Overview

Journal PeerJ

Specialties Biology
Environmental Health
General Medicine

Date 2019 Oct 23

PMID 31637126

Citations 20

Authors

Jiankui Liu

Chunhua Wei

Zhifeng Lin

Wei Xia

Ying Ma

Ailing Dai

Xiaoyan Yang

Affiliations

Soon will be listed here.

Abstract

PRRS virus (PRRSV) has undergone rapid evolution and resulted in immense economic losses worldwide. In the present study, a PRRSV strain named FJ0908 causing high abortion rate (25%) and mortality (40%) was detected in a swine herd in China. To determine if a new PRRSV genotype had emerged, we characterized the genetic characteristics of FJ0908. Phylogenetic analysis indicated that FJ0908 was related to 1-7-4-like strains circulating in the United States since 2014. Furthermore, the ORF5 sequence restriction fragment length polymorphism (RFLP) pattern of FJ0908 was 1-7-4. Additionally, FJ0908 had a 100 aa deletion (aa329-428) within nsp2, as compared to VR-2332, and the deletion pattern was consistent with most of 1-7-4 PRRSVs. Collectively, the data of this study contribute to the understanding of 1-7-4-like PRRSV molecular epidemiology in China.

Citing Articles

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