Usefulness of Histologic Differences and Perivascular Infiltration for Preoperative T Staging of Advanced Gastric Cancer Using Computed Tomography

Overview

Journal Jpn J Radiol

Publisher Springer

Specialty Radiology

Date 2019 Oct 19

PMID 31625013

Authors

Ji Youn Kim

Woo-Suk Chung

Hyeun Jin Lee

Ji Hae An

Jang Shin Son

Affiliations

Soon will be listed here.

Abstract

Purpose: This study aimed to determine whether histologic differences and perivascular infiltration are useful for clinical T staging of advanced gastric cancer (AGC).

Materials And Methods: This retrospective study included 160 patients with pathologically confirmed AGC who had available preoperative stomach computed tomography (CT). Using stomach CT, they were classified according to standard T stage, histologic T stage, and perivascular T stage. Accuracy of each T stage criteria was analyzed. Perivascular infiltrations for the evaluation of prognosis were correlated with time to tumor progression by log-rank test.

Results: There was a significant difference between the accuracies of the standard and histologic T stages (p < 0.001), whereas there was no significant difference between the standard and perivascular T stages (p = 0.07). In 121 patients who were pathologically confirmed as having T3 or T4a tumor, there was a significant difference between the standard and perivascular T stage (p < 0.001). In patients having T3 or T4a tumor, time to tumor progression of the negative perivascular infiltration subgroup was significantly longer than the positive subgroup.

Conclusion: Consideration of histologic differences and perivascular infiltration may be useful for clinical T staging of AGC.

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