Fumigant Antifungal Activity Via Reactive Oxygen Species of and Essential Oils and Constituents Against and

Overview

Journal Biomolecules

Publisher MDPI

Specialties Biochemistry
Molecular Biology

Date 2019 Oct 19

PMID 31623331

Citations 11

Authors

Jeong-Eun Kim

Ji-Eun Lee

Min-Jung Huh

Sung-Chan Lee

Seon-Mi Seo

Jun Hyeong Kwon

Il-Kwon Park

Affiliations

Soon will be listed here.

Abstract

In this study, the fumigant antifungal activity of 10 Lamiaceae plant essential oils was evaluated against two phytopathogenic fungi, and Among the tested essential oils, thyme white () and summer savory () essential oils exhibited the strongest fumigant antifungal activity against the phytopathogenic fungi. We analyzed the chemical composition of two active essential oils and tested the fumigant antifungal activities of the identified compounds. Among the tested compounds, thymol and carvacrol had potent fumigant antifungal activity. We observed reactive oxygen species (ROS) generation in two fungi treated with thymol and carvacrol. Confocal laser scanning microscopy images of fungi stained with propidium iodide showed that thymol and carvacrol disrupted fungal cell membranes. Our results indicated that ROS generated by thymol and carvacrol damaged the cell membrane of and , causing cell death.

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