Concurrent Fusobacterial Pyogenic Liver Abscess and Empyema

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2019 Oct 17

PMID 31615779

Citations 9

Authors

Ahmed Gohar

Fady Jamous

Mohamed Abdallah

Affiliations

Soon will be listed here.

Abstract

We present a very rare case of concurrent empyema and liver abscess caused by Fusobacterium. Our patient presented with 3-month history of subtle abdominal discomfort and cough leading to eventually presenting with marked chest pain, dyspnoea and septic shock. CT revealed a liver abscess and large right-sided pleural effusion. Drainage of the pleural effusion yielded gross pus with the growth of , while drainage of the liver abscess yielded The patient responded to drainage and antibiotic therapy with resolution of symptoms and decrease in the size of empyema and abscess on follow-up imaging. We also include a review if literature of related fusobacterial infections.

Citing Articles

Unraveling a Unique Encounter of Fusobacterium nucleatum With Empyema: A Case Report and Review of Literature.

Sanivarapu R, Rajamreddy R, Kosaraju A Cureus. 2023; 15(7):e42488.

PMID: 37637529 PMC: 10453982. DOI: 10.7759/cureus.42488.

Vertebral osteomyelitis caused by with an associated asymptomatic liver abscess in an immunocompetent adult: A case report and literature review.

Toyoshima H, Tanigawa M, Ishiguro C, Tanaka H, Nakanishi Y, Sakabe S IDCases. 2023; 32:e01754.

PMID: 37096206 PMC: 10121789. DOI: 10.1016/j.idcr.2023.e01754.

Pleural empyema secondary to perforated diverticulosis due to biliary neoplasia infiltration.

Dawid de Vera M, Prieto Cuadra J, Dominguez Pinos D, Hierro Martin I BMJ Case Rep. 2023; 16(3).

PMID: 36898708 PMC: 10008382. DOI: 10.1136/bcr-2022-250061.

Clinical Characteristics of Diabetes Complicated by Bacterial Liver Abscess and Nondiabetes-Associated Liver Abscess.

Wang F, Yu J, Chen W, Mo Z, Zhang Y Dis Markers. 2022; 2022:7512736.

PMID: 35521637 PMC: 9064492. DOI: 10.1155/2022/7512736.

and : Hepatic Abscesses in a Healthy Soldier.

Strobel S, Whitaker D, Choi E, Lindow J, Lago K Case Rep Infect Dis. 2022; 2022:5500365.

PMID: 35345475 PMC: 8957035. DOI: 10.1155/2022/5500365.

References

Wrightson J, Wray J, Street T, Chapman S, Gleeson F, Maskell N . Absence of Atypical Pathogens in Pleural Infection. Chest. 2015; 148(3):e102-e103. DOI: 10.1378/chest.15-1130. View

Moores D . Management of acute empyema. Chest. 1992; 102(5):1316-7. DOI: 10.1378/chest.102.5.1316. View

Bennett K, Eley A . Fusobacteria: new taxonomy and related diseases. J Med Microbiol. 1993; 39(4):246-54. DOI: 10.1099/00222615-39-4-246. View

Karantanos T, Karanika S, Obiokoye K, Sullivan M, Phillips C, Ananthakrishnan S . Pyogenic Liver Abscess Due to Fusobacterium nucleatum in a Patient With Liver Hemangiomas. Am J Med Sci. 2017; 353(4):417-418. DOI: 10.1016/j.amjms.2016.07.008. View

Rashidi A, Tahhan S, Cohee M, Goodman B . Fusobacterium nucleatum infection mimicking metastatic cancer. Indian J Gastroenterol. 2012; 31(4):198-200. DOI: 10.1007/s12664-012-0233-x. View

Riordan T . Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome. Clin Microbiol Rev. 2007; 20(4):622-59. PMC: 2176048. DOI: 10.1128/CMR.00011-07. View

Bhatnagar R, Maskell N . Treatment of complicated pleural effusions in 2013. Clin Chest Med. 2013; 34(1):47-62. DOI: 10.1016/j.ccm.2012.11.004. View

Hockensmith M, Mellman D, Aronsen E . Fusobacterium nucleatum empyema necessitans. Clin Infect Dis. 1999; 29(6):1596-8. DOI: 10.1086/313553. View

Ahmed Z, Bansal S, Dhillon S . Pyogenic liver abscess caused by Fusobacterium in a 21-year-old immunocompetent male. World J Gastroenterol. 2015; 21(12):3731-5. PMC: 4375599. DOI: 10.3748/wjg.v21.i12.3731. View

10.

David H . A 21-year-old man with fever and abdominal pain after recent peritonsillar abscess drainage. Am J Emerg Med. 2009; 27(4):515.e3-4. DOI: 10.1016/j.ajem.2008.07.043. View

11.

Waqas S, Bannan C, Talento A, Byrne D, OConnell S, Clarke S . A Unique Case of Concurrent Long Bone Osteomyelitis and Empyema Caused by Fusobacterium nucleatum. Ir Med J. 2018; 111(1):675. View

12.

Maskell N, Batt S, Hedley E, Davies C, Gillespie S, Davies R . The bacteriology of pleural infection by genetic and standard methods and its mortality significance. Am J Respir Crit Care Med. 2006; 174(7):817-23. DOI: 10.1164/rccm.200601-074OC. View

13.

Kaplan G, Gregson D, Laupland K . Population-based study of the epidemiology of and the risk factors for pyogenic liver abscess. Clin Gastroenterol Hepatol. 2004; 2(11):1032-8. DOI: 10.1016/s1542-3565(04)00459-8. View

14.

Meddings L, Myers R, Hubbard J, Shaheen A, Laupland K, Dixon E . A population-based study of pyogenic liver abscesses in the United States: incidence, mortality, and temporal trends. Am J Gastroenterol. 2009; 105(1):117-24. DOI: 10.1038/ajg.2009.614. View

15.

Boots R, Windsor M . Missed foreign body and nessitans empyema. Anaesth Intensive Care. 2007; 35(6):971-4. DOI: 10.1177/0310057X0703500620. View

16.

Bedawi E, Hassan M, Rahman N . Recent developments in the management of pleural infection: A comprehensive review. Clin Respir J. 2018; 12(8):2309-2320. DOI: 10.1111/crj.12941. View

17.

Wijarnpreecha K, Yuklyaeva N, Sornprom S, Hyman C . Fusobacterium Nucleatum: Atypical Organism of Pyogenic Liver Abscess Might be Related to Sigmoid Diverticulitis. N Am J Med Sci. 2016; 8(4):197-9. PMC: 4866478. DOI: 10.4103/1947-2714.179961. View

18.

Kearney A, Knoll B . Myopericarditis associated with Fusobacterium nucleatum-caused liver abscess. Infect Dis (Lond). 2014; 47(3):187-9. DOI: 10.3109/00365548.2014.969306. View

19.

Kajiya T, Uemura T, Kajiya M, Kaname H, Hirano R, Uemura N . Pyogenic liver abscess related to dental disease in an immunocompetent host. Intern Med. 2008; 47(7):675-8. DOI: 10.2169/internalmedicine.47.0638. View

20.

Nagpal S, Mukhija D, Patel P . Fusobacterium nucleatum: a rare cause of pyogenic liver abscess. Springerplus. 2015; 4:283. PMC: 4472653. DOI: 10.1186/s40064-015-1090-8. View