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Pneumonitis Due to Oren-gedoku-to (Coptis Detoxifying Decoction)

Overview
Journal Intern Med
Specialty General Medicine
Date 2019 Oct 16
PMID 31611510
Citations 1
Authors
Naoto Mochizuki
Satoshi Ano
Norihiro Kikuchi
Chio Sakai
Michiko Masuda
Yuzuru Kondo
Yukio Ishii
Affiliations
Soon will be listed here.
Abstract

A 54-year-old man started to take oren-gedoku-to (coptis detoxifying decoction) because he was experiencing chronic hot flashes, night sweats and insomnia. He developed a high fever from the day of intake. At day 17, he stopped taking oren-gedoku-to because of malaise and chills, and he was admitted to our hospital. Drug-induced pneumonitis was suspected, and all drugs were stopped. Consequently, his symptoms, laboratory data and chest X-ray findings markedly improved. The results of a lymphocyte stimulation test were positive for oren-gedoku-to and one of its components, ougon (Baikal skullcap). Based on these findings, we diagnosed him with pneumonitis caused by ougon.

Citing Articles

Immune-Related Adverse Events due to Concomitant Use of Immune Checkpoint Inhibitors and Chinese Herbal Medicines: A Study Based on a Japanese Adverse Event Database.

Koshiishi T, Nishioka N, Yoshimoto K Asian Pac J Cancer Prev. 2024; 25(7):2291-2295.

PMID: 39068560 PMC: 11480620. DOI: 10.31557/APJCP.2024.25.7.2291.

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