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Structural Biology of the TGFβ Family

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Specialty Biology
Date 2019 Oct 10
PMID 31594405
Citations 20
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References
1.
Wang R, Zhu J, Dong X, Shi M, Lu C, Springer T . GARP regulates the bioavailability and activation of TGFβ. Mol Biol Cell. 2012; 23(6):1129-39. PMC: 3302739. DOI: 10.1091/mbc.E11-12-1018. View

2.
Wu J, Krawitz A, Chai J, Li W, Zhang F, Luo K . Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling. Cell. 2002; 111(3):357-67. DOI: 10.1016/s0092-8674(02)01006-1. View

3.
Shi Y, Hata A, Lo R, Massague J, Pavletich N . A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature. 1997; 388(6637):87-93. DOI: 10.1038/40431. View

4.
Gao Y, Vincent D, Davis A, Sansom O, Bartholin L, Li Q . Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis. Oncotarget. 2016; 7(27):40904-40918. PMC: 5173031. DOI: 10.18632/oncotarget.10149. View

5.
Brunet L, McMahon J, McMahon A, Harland R . Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science. 1998; 280(5368):1455-7. DOI: 10.1126/science.280.5368.1455. View