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The Gastroenterologist's Guide to Preventive Management of Compensated Cirrhosis

Overview
Specialty Gastroenterology
Date 2019 Oct 9
PMID 31592079
Citations 7
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Abstract

Despite advances in medical care, the prevalence and mortality associated with cirrhosis continue to rise. The majority of medical care and physician efforts are devoted to the management of decompensated cirrhosis and its complications of gastrointestinal hemorrhage, hepatic encephalopathy, and ascites; however, limited efforts are placed on the medical management of compensated cirrhosis. Patients with compensated cirrhosis carry a higher survival rate, and, when diagnosed early, may be screened for future decompensation. When possible, these patients can be treated for their underlying disease to prevent disease progression and avoid the need for liver transplantation. This article reviews the importance of early diagnosis, outpatient management of compensated cirrhosis, early screening for potential decompensation, and patient education.

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References
1.
Fuster D, Samet J . Alcohol Use in Patients with Chronic Liver Disease. N Engl J Med. 2018; 379(26):2579. DOI: 10.1056/NEJMc1814129. View

2.
Gupta S, Bent S, Kohlwes J . Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysis. Ann Intern Med. 2003; 139(1):46-50. DOI: 10.7326/0003-4819-139-1-200307010-00012. View

3.
Gronkjaer L, Vilstrup H . Oral health in patients with liver cirrhosis. Eur J Gastroenterol Hepatol. 2015; 27(7):834-9. DOI: 10.1097/MEG.0000000000000356. View

4.
Bal C, Bhatia V, Kumar S, Saini D, Khillan V, Gupta E . Influenza A/H1/N1/09 infection in patients with cirrhosis has a poor outcome: a case series. Indian J Gastroenterol. 2014; 33(2):178-82. DOI: 10.1007/s12664-014-0443-5. View

5.
Gluud L, Krag A . Banding ligation versus beta-blockers for primary prevention in oesophageal varices in adults. Cochrane Database Syst Rev. 2012; (8):CD004544. PMC: 11382336. DOI: 10.1002/14651858.CD004544.pub2. View