The In-vitro Activity of Some Antimicrobial Agents Against Methicillin-resistant Staphylococcus Aureus

Overview

Journal J Antimicrob Chemother

Publisher Oxford University Press

Specialty Infectious Diseases

Date 1985 Mar 1

PMID 3158632

Citations 5

Authors

E C Moorhouse

T E Mulvihill

L Jones

D Mooney

F R Falkiner

C T Keane

Affiliations

Soon will be listed here.

Abstract

A total of 185 strains of methicillin resistant Staphylococcus aureus was investigated for sensitivity to five other antimicrobial agents. The vast majority of these strains were also resistant to gentamicin and fusidic acid. Rifampicin was the most active drug tested (MIC90, 0.007 mg/l), while two newer compounds teichomycin and ciprofloxacin showed equal and appreciable activity (MIC90, 0.5 mg/l).

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Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Monk J, Price A, Benfield P, Todd P, Ward A Drugs. 1988; 35(4):373-447.

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Ciprofloxacin therapy of experimental endocarditis caused by methicillin-susceptible or methicillin-resistant Staphylococcus aureus.

Fernandez-Guerrero M, Rouse M, Henry N, Wilson W Antimicrob Agents Chemother. 1988; 32(5):747-51.

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Fluoroquinolone antimicrobial agents.

Wolfson J, Hooper D Clin Microbiol Rev. 1989; 2(4):378-424.

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Ciprofloxacin-resistant methicillin-resistant Staphylococcus aureus in an acute-care hospital.

Raviglione M, Boyle J, Mariuz P, Pablos-Mendez A, Cortes H, Merlo A Antimicrob Agents Chemother. 1990; 34(11):2050-4.

PMID: 2073096 PMC: 171997. DOI: 10.1128/AAC.34.11.2050.