» Articles » PMID: 31579783

Utilization of Indocynanine Green Fluorescent Imaging (ICG-FI) for the Assessment of Microperfusion in Vascular Medicine

Overview
Journal Innov Surg Sci
Publisher De Gruyter
Specialty General Surgery
Date 2019 Oct 4
PMID 31579783
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

Intraoperative valuation of organ and tissue microperfusion is always a current topic in different surgical situations. Although indocyanine green fluorescent imaging (ICG-FI) has turned to be a more and more common technique to evaluate organ perfusion, only few studies tried to quantitatively validate the technique for microperfusion assessment. The aim of the following manuscript is to present the results of our interdisciplinary research confirming additional quantitative assessment tools in different surgical conditions. Thus, we are implementing the background-subtracted peak fluorescent intensity (BSFI), the slope of fluorescence intensity (SFI), and the time to slope (TTS) using ICG-FI in several regions of interest (ROI).

Citing Articles

The Medical Basis for the Photoluminescence of Indocyanine Green.

Mytych W, Bartusik-Aebisher D, Aebisher D Molecules. 2025; 30(4).

PMID: 40005197 PMC: 11858079. DOI: 10.3390/molecules30040888.


Use of Indocyanine Green (ICG) to Assess Myocardial Perfusion and Territorial Distribution of Vein Grafts Implanted on Coronary Arteries in an Porcine Model. A Potential Adjunct to Assist Revascularization Strategies and Training in Coronary Artery....

Spadaccio C, Nenna A, Corrado D, Glenn C, Panza A, Vester R Rev Cardiovasc Med. 2025; 26(1):25778.

PMID: 39867206 PMC: 11759963. DOI: 10.31083/RCM25778.


NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery.

Depalma N, DUgo S, Manoochehri F, Libia A, Sergi W, Marchese T Cancers (Basel). 2023; 15(23).

PMID: 38067233 PMC: 10705733. DOI: 10.3390/cancers15235528.


The Wonder Dye: Uses and Implications of Indigocyanine Green in Various Surgeries.

Rahate N, Kapse A, Rahate P, Nimbhorkar S Cureus. 2023; 15(10):e46722.

PMID: 38021982 PMC: 10630983. DOI: 10.7759/cureus.46722.


Real-time quantification of bowel perfusion using Laparoscopic Laser Speckle Contrast Imaging (LSCI) in a porcine model.

Mehrotra S, Liu Y, Nwaiwu C, Buharin V, Stolyarov R, Schwaitzberg S BMC Surg. 2023; 23(1):261.

PMID: 37649010 PMC: 10468884. DOI: 10.1186/s12893-023-02161-w.


References
1.
Shimada Y, Okumura T, Nagata T, Sawada S, Matsui K, Hori R . Usefulness of blood supply visualization by indocyanine green fluorescence for reconstruction during esophagectomy. Esophagus. 2012; 8(4):259-266. PMC: 3339581. DOI: 10.1007/s10388-011-0291-7. View

2.
Desai N, Miwa S, Kodama D, Cohen G, Christakis G, Goldman B . Improving the quality of coronary bypass surgery with intraoperative angiography: validation of a new technique. J Am Coll Cardiol. 2005; 46(8):1521-5. DOI: 10.1016/j.jacc.2005.05.081. View

3.
Behrendt F, Tolba R, Overhaus M, Hirner A, Minor T, Kalff J . Indocyanine green fluorescence measurement of intestinal transit and gut perfusion after intestinal manipulation. Eur Surg Res. 2004; 36(4):210-8. DOI: 10.1159/000078855. View

4.
Detter C, Russ D, Iffland A, Wipper S, Schurr M, Reichenspurner H . Near-infrared fluorescence coronary angiography: a new noninvasive technology for intraoperative graft patency control. Heart Surg Forum. 2003; 5(4):364-9. View

5.
Desai N, Miwa S, Kodama D, Koyama T, Cohen G, Pelletier M . A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. J Thorac Cardiovasc Surg. 2006; 132(3):585-94. DOI: 10.1016/j.jtcvs.2005.09.061. View