Virulence Factors and Antibiotic Resistance of Avian Pathogenic in Eastern China

Overview

Journal J Vet Res

Publisher Sciendo

Specialty Veterinary Medicine

Date 2019 Oct 2

PMID 31572810

Citations 14

Authors

Xiaojing Xu

Qing Sun

Lixiang Zhao

Affiliations

Soon will be listed here.

Abstract

Introduction: Avian pathogenic (APEC) causes serious colibacillosis and significant economic losses. Data on profiles of virulence factors and antibiotic resistances among APEC strains are crucial to the control of infection. In this study, strains were isolated from eastern China, and the prevalence of virulence factors and distribution of antibiotic resistance were determined.

Material And Methods: APEC strains were isolated and characterised by PCR for O serogroups, virulence factor genes, antibiotic resistance, and phylogenetic groups.

Results: O78 was the most prevalent serogroup and type A was the most frequent phylogenetic group. The,, and genes were the most prevalent among the isolates. All isolates were multiresistant, and all strains were resistant to ampicillin and tetracycline, which are widely used in the poultry industry in China.

Conclusion: This study provided important data on the presence of virulence genes and antibiotic resistance profiles of APEC from poultry farms in eastern China.

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References

Ramadan H, Awad A, Ateya A . Detection of phenotypes, virulence genes and phylotypes of avian pathogenic and human diarrheagenic Escherichia coli in Egypt. J Infect Dev Ctries. 2016; 10(6):584-91. DOI: 10.3855/jidc.7762. View

Ewers C, Janssen T, Kiessling S, Philipp H, Wieler L . Molecular epidemiology of avian pathogenic Escherichia coli (APEC) isolated from colisepticemia in poultry. Vet Microbiol. 2004; 104(1-2):91-101. DOI: 10.1016/j.vetmic.2004.09.008. View

Ghunaim H, Abu-Madi M, Kariyawasam S . Advances in vaccination against avian pathogenic Escherichia coli respiratory disease: potentials and limitations. Vet Microbiol. 2014; 172(1-2):13-22. DOI: 10.1016/j.vetmic.2014.04.019. View

Oliveira A, Sereno R, Azeredo J . In vivo efficiency evaluation of a phage cocktail in controlling severe colibacillosis in confined conditions and experimental poultry houses. Vet Microbiol. 2010; 146(3-4):303-8. DOI: 10.1016/j.vetmic.2010.05.015. View

Zhao L, Gao S, Huan H, Xu X, Zhu X, Yang W . Comparison of virulence factors and expression of specific genes between uropathogenic Escherichia coli and avian pathogenic E. coli in a murine urinary tract infection model and a chicken challenge model. Microbiology (Reading). 2009; 155(Pt 5):1634-1644. DOI: 10.1099/mic.0.024869-0. View

Oosterik L, Peeters L, Mutuku I, Goddeeris B, Butaye P . Susceptibility of avian pathogenic Escherichia coli from laying hens in Belgium to antibiotics and disinfectants and integron prevalence. Avian Dis. 2014; 58(2):271-8. DOI: 10.1637/10680-100113-RegR. View

Zhao S, Maurer J, Hubert S, De Villena J, McDermott P, Meng J . Antimicrobial susceptibility and molecular characterization of avian pathogenic Escherichia coli isolates. Vet Microbiol. 2005; 107(3-4):215-24. DOI: 10.1016/j.vetmic.2005.01.021. View

Obaid J, Mansour S, Elshahedy M, Rabie T, Azab A . Uropathogenic Escherichia coli isolates with different virulence genes content exhibit similar pathologic influence on Vero cells. Pol J Microbiol. 2014; 63(1):43-9. View

Krishnasamy V, Otte J, Silbergeld E . Antimicrobial use in Chinese swine and broiler poultry production. Antimicrob Resist Infect Control. 2015; 4:17. PMC: 4412119. DOI: 10.1186/s13756-015-0050-y. View

10.

Chaudhari A, Kariyawasam S . An experimental infection model for Escherichia coli egg peritonitis in layer chickens. Avian Dis. 2014; 58(1):25-33. DOI: 10.1637/10536-032213-Reg.1. View

11.

Cremet L, Broquet A, Jacqueline C, Chaillou C, Asehnoune K, Corvec S . Innate immune evasion of Escherichia coli clinical strains from orthopedic implant infections. Eur J Clin Microbiol Infect Dis. 2016; 35(6):993-9. DOI: 10.1007/s10096-016-2628-6. View

12.

Li Y, Chen L, Wu X, Huo S . Molecular characterization of multidrug-resistant avian pathogenic Escherichia coli isolated from septicemic broilers. Poult Sci. 2015; 94(4):601-11. DOI: 10.3382/ps/pev008. View