Patent Ductus Arteriosus in Preterm Infants: is Early Transcatheter Closure a Paradigm Shift?

Overview

Journal J Perinatol

Specialty Gynecology & Obstetrics

Date 2019 Sep 29

PMID 31562396

Citations 10

Authors

P Vali

S Lakshminrusimha

A Pelech

M Underwood

F Ing

Affiliations

Soon will be listed here.

Abstract

The optimal management approach of the patent ductus arteriosus (PDA) in premature infants remains uncertain owing the lack of evidence for long-term benefits and the limited analyses of the complications of medical and surgical interventions to date. In recent years, devices suitable to plug the PDA of premature infants (including extremely low birthweight, <1000 g) have become available and several trials have demonstrated successful and safe transcatheter PDA closure (TCPC) in this population. Whether TCPC represents a paradigm shift in PDA management that will result in improved short- and long-term outcomes, less bronchopulmonary dysplasia, improved neurodevelopment, or better long term renal function remains to be seen. Careful rigorous study of the potential benefits of TCPC in this highly vulnerable population in the context of well-designed adequately powered trials is needed prior to widespread adoption of this approach.

Citing Articles

A Global Perspective on PDA Management in the Extremely Premature: Shifting Trend Toward Transcatheter Closure.

Sathanandam S, McNamara P, Pedra C, Toyoshima K, Malekzadeh-Milani S, Patkai J J Soc Cardiovasc Angiogr Interv. 2024; 2(4):100968.

PMID: 39131651 PMC: 11307882. DOI: 10.1016/j.jscai.2023.100968.

Morbidity and neurodevelopmental outcomes at 2 years in preterm infants undergoing percutaneous transcatheter closure vs. surgical ligation of the PDA.

Fernandez M, Kase J, Giamelli J, Reichlin A J Perinatol. 2024; 44(10):1454-1462.

PMID: 38831120 DOI: 10.1038/s41372-024-02019-w.

Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment.

Huang X, Han D, Wei Y, Lin B, Zeng D, Zhang Y Front Pediatr. 2022; 10:919879.

PMID: 35958170 PMC: 9361044. DOI: 10.3389/fped.2022.919879.

The ductus arteriosus in neonates with critical congenital heart disease.

Wheeler C, Sen S, Levy P J Perinatol. 2022; 42(12):1708-1713.

PMID: 35840708 DOI: 10.1038/s41372-022-01449-8.

Left Vocal Cord Paralysis, Lung Function and Exercise Capacity in Young Adults Born Extremely Preterm With a History of Neonatal Patent Ductus Arteriosus Surgery-A National Cohort Study.

Engan M, Engeset M, Sandvik L, Gamlemshaug O, Engesaeter I, Oymar K Front Pediatr. 2022; 9:780045.

PMID: 35047462 PMC: 8761768. DOI: 10.3389/fped.2021.780045.

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