The Canine Morbillivirus Strain Associated with An Epizootic in Caspian Seals Provides New Insights into the Evolutionary History of This Virus

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2019 Sep 28

PMID 31557833

Citations 17

Authors

Wendy K Jo

Martin Peters

Aidyn Kydyrmanov

Marco W G van de Bildt

Thijs Kuiken

Albert Osterhaus

Martin Ludlow

Affiliations

Soon will be listed here.

Abstract

Canine morbillivirus (canine distemper virus; CDV) is a worldwide distributed morbillivirus that causes sporadic cases and recurrent epizootics among an increasing number of wild, feral, and domestic animal species. We investigated the evolutionary history of CDV strains involved in the 1988 Lake Baikal (CDVPS88) and the 2000 Caspian Sea (CDVPC00) seal die-offs by recovery of full-length sequences from archived material using next-generation sequencing. Bayesian phylogenetic analyses indicated that CDVPC00 constitutes a novel strain in a separate clade (tentatively termed "Caspian") from the America-1 clade, which is comprised of older vaccine strains. The America-1/Caspian monophyletic group is positioned most basally with respect to other clades and is estimated to have separated from other CDV clades around 1832. Our results indicate that CDVPC00 recovered from the epizootic in the Caspian Sea in 2000 belongs to a previously undetected novel clade and constitutes the most ancestral wild-type CDV clade.

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References

Tatsuo H, Ono N, Yanagi Y . Morbilliviruses use signaling lymphocyte activation molecules (CD150) as cellular receptors. J Virol. 2001; 75(13):5842-50. PMC: 114299. DOI: 10.1128/JVI.75.13.5842-5850.2001. View

Sawatsky B, Wong X, Hinkelmann S, Cattaneo R, von Messling V . Canine distemper virus epithelial cell infection is required for clinical disease but not for immunosuppression. J Virol. 2012; 86(7):3658-66. PMC: 3302517. DOI: 10.1128/JVI.06414-11. View

Bhatt M, Rajak K, Chakravarti S, Yadav A, Kumar A, Gupta V . Phylogenetic analysis of haemagglutinin gene deciphering a new genetically distinct lineage of canine distemper virus circulating among domestic dogs in India. Transbound Emerg Dis. 2019; 66(3):1252-1267. DOI: 10.1111/tbed.13142. View

Kapil S, Allison R, Johnston 3rd L, Murray B, Holland S, Meinkoth J . Canine distemper virus strains circulating among North American dogs. Clin Vaccine Immunol. 2008; 15(4):707-12. PMC: 2292659. DOI: 10.1128/CVI.00005-08. View

Zhang X, Lu G, Qi J, Li Y, He Y, Xu X . Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4. Nat Struct Mol Biol. 2012; 20(1):67-72. DOI: 10.1038/nsmb.2432. View

Jo W, Kruppa J, Habierski A, van de Bildt M, Mazzariol S, Di Guardo G . Evolutionary evidence for multi-host transmission of cetacean morbillivirus. Emerg Microbes Infect. 2018; 7(1):201. PMC: 6279766. DOI: 10.1038/s41426-018-0207-x. View

Kennedy S, Kuiken T, Jepson P, Deaville R, Forsyth M, Barrett T . Mass die-Off of Caspian seals caused by canine distemper virus. Emerg Infect Dis. 2000; 6(6):637-9. PMC: 2640919. DOI: 10.3201/eid0606.000613. View

Namroodi S, Rostami A, Majidzadeh-Ardebili K, Ghalyanchi Langroudi A, Morovvati A . Detection of Arctic and European cluster of canine distemper virus in north and center of Iran. Vet Res Forum. 2016; 6(3):199-204. PMC: 4611972. View

von Messling V, Milosevic D, Cattaneo R . Tropism illuminated: lymphocyte-based pathways blazed by lethal morbillivirus through the host immune system. Proc Natl Acad Sci U S A. 2004; 101(39):14216-21. PMC: 521139. DOI: 10.1073/pnas.0403597101. View

10.

. Distemper virus in Baikal seals. Nature. 1989; 338(6212):209-10. DOI: 10.1038/338209a0. View

11.

Zhao J, Yan X, Chai X, Martella V, Luo G, Zhang H . Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from breeding foxes, raccoon dogs and minks in China. Vet Microbiol. 2009; 140(1-2):34-42. DOI: 10.1016/j.vetmic.2009.07.010. View

12.

Appel M, Reggiardo C, Summers B, MARE C, Noon T, Reed R . Canine distemper virus infection and encephalitis in javelinas (collared peccaries). Arch Virol. 1991; 119(1-2):147-52. DOI: 10.1007/BF01314331. View

13.

Ek-Kommonen C, Sihvonen L, Pekkanen K, Rikula U, Nuotio L . Outbreak off canine distemper in vaccinated dogs in Finland. Vet Rec. 1997; 141(15):380-3. DOI: 10.1136/vr.141.15.380. View

14.

Blancou J . Dog distemper: imported into Europe from South America?. Hist Med Vet. 2004; 29(2):35-41. View

15.

Sakai K, Nagata N, Ami Y, Seki F, Suzaki Y, Iwata-Yoshikawa N . Lethal canine distemper virus outbreak in cynomolgus monkeys in Japan in 2008. J Virol. 2012; 87(2):1105-14. PMC: 3554058. DOI: 10.1128/JVI.02419-12. View

16.

Rieux A, Balloux F . Inferences from tip-calibrated phylogenies: a review and a practical guide. Mol Ecol. 2016; 25(9):1911-24. PMC: 4949988. DOI: 10.1111/mec.13586. View

17.

Mamaev L, Denikina N, Belikov S, Volchkov V, Visser I, Fleming M . Characterisation of morbilliviruses isolated from Lake Baikal seals (Phoca sibirica). Vet Microbiol. 1995; 44(2-4):251-9. DOI: 10.1016/0378-1135(95)00018-6. View

18.

Riley M, Wilkes R . Sequencing of emerging canine distemper virus strain reveals new distinct genetic lineage in the United States associated with disease in wildlife and domestic canine populations. Virol J. 2015; 12:219. PMC: 4683949. DOI: 10.1186/s12985-015-0445-7. View

19.

Stamatakis A . RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. Bioinformatics. 2014; 30(9):1312-3. PMC: 3998144. DOI: 10.1093/bioinformatics/btu033. View

20.

Dudas G, Bedford T . The ability of single genes vs full genomes to resolve time and space in outbreak analysis. BMC Evol Biol. 2019; 19(1):232. PMC: 6933756. DOI: 10.1186/s12862-019-1567-0. View