The Effects of Feeding Yeast Bioactives to Broiler Breeders And/or Their Offspring on Growth Performance, Gut Development, and Immune Function in Broiler Chickens Challenged with Eimeria

Overview

Journal Poult Sci

Publisher Elsevier

Specialty Veterinary Medicine

Date 2019 Sep 11

PMID 31504867

Citations 12

Authors

Z Lu

A Thanabalan

H Leung

R Akbari Moghaddam Kakhki

R Patterson

E G Kiarie

Affiliations

Soon will be listed here.

Abstract

Yeast bioactives (YB) may stimulate broiler breeders (BB) to increase deposition of immunoglobulins (Ig) in eggs. We investigated the effects of feeding YB (mixture of derivatives from whole yeast subjected to enzymatic hydrolysis) to BB and/or their offspring on growth performance, gut development, and immune function in broiler chickens challenged with Eimeria. The BB (Ross 708 ♀ and Ross ♂) were assigned to 2 groups (60 ♀ and 10 ♂) and fed basal or basal diet supplemented with 500 g of YB/Mt. A total of 250 fertile eggs per treatment were collected, incubated, hatched, and sexed. Additional egg samples were analyzed for IgA and IgY contents. A total of 160 broiler chicks (80 ♀ and 80 ♂) from each breeder experimental group were placed in cages based on sex and BW resulting in 32 cages for each BB treatment group. Cages (16 per BB treatment group) were allocated to basal broiler chick diet or basal diet supplemented with 500 g of YB/Mt. On day 9, half of each BB by broiler chick dietary treatments was challenged with 1 mL of Eimeria culture (100,000 oocysts of Eimeria acervulina and 25,000 oocysts of Eimeria maxima). On day 14, all birds were necropsied for intestinal lesion scores and samples. Feeding YB to BB increased (P < 0.05) IgA concentration in egg yolk. Eimeria challenge decreased (P < 0.05) pancreas weight, jejunal villus height (VH), and growth performance but increased spleen weight, intestinal mass and jejunal mucosa IgA concentration. Independent of Eimeria challenge, feeding YB to BB and/or to chicks resulted in higher (P < 0.001) jejunal VH compared with feeding it to BB only or not at all. In conclusion, Eimeria challenge reduced growth performance and had negative effects on indices of intestinal function and health. Feeding YB to BB increased deposition of IgA in hatching eggs and improved jejunal VH independent of Eimeria challenge when fed to BB and/or to broiler chicks.

Citing Articles

Effects of lifetime feeding of hydrolyzed yeast to broiler breeders on egg production, quality, and hatchling attributes.

Maina A, Schulze H, Kiarie E Poult Sci. 2025; 104(2):104826.

PMID: 39848209 PMC: 11795560. DOI: 10.1016/j.psj.2025.104826.

Effect of a probiotic mixture with lactic acid activity on productive and allometric indicators in broiler chickens.

Gonzalez S, Sandoval L, Giovanny T Vet World. 2024; 17(7):1490-1496.

PMID: 39185053 PMC: 11344101. DOI: 10.14202/vetworld.2024.1490-1496.

Feeding a Novel Mannan-Rich Yeast Carbohydrate Product Improves Production Performance and Humoral Immunity of Broiler Chickens.

Wang A, Archile A, Patterson R Animals (Basel). 2024; 14(11).

PMID: 38891714 PMC: 11171193. DOI: 10.3390/ani14111667.

Significance of successive feeding of sources of n-3 fatty acids to broiler breeders and their progeny on growth performance, intestinal lesion scores, lymphoid organs weight and plasma immunoglobulin A in broiler chickens challenged with Eimeria.

Thanabalan A, Dreger R, Kiarie E Poult Sci. 2024; 103(7):103796.

PMID: 38776857 PMC: 11141267. DOI: 10.1016/j.psj.2024.103796.

Response of broiler breeder pullets when fed hydrolyzed whole yeast from placement to 22 wk of age.

Maina A, Schulze H, Kiarie E Poult Sci. 2024; 103(3):103383.

PMID: 38176370 PMC: 10806125. DOI: 10.1016/j.psj.2023.103383.

References

Niewold T . The nonantibiotic anti-inflammatory effect of antimicrobial growth promoters, the real mode of action? A hypothesis. Poult Sci. 2007; 86(4):605-9. DOI: 10.1093/ps/86.4.605. View

Gadde U, Kim W, Oh S, Lillehoj H . Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review. Anim Health Res Rev. 2017; 18(1):26-45. DOI: 10.1017/S1466252316000207. View

Rose M, ORLANS E, Buttress N . Immunoglobulin classes in the hen's egg: their segregation in yolk and white. Eur J Immunol. 1974; 4(7):521-3. DOI: 10.1002/eji.1830040715. View

Major Jr J, Ruff M . Eimeria spp.: influence of coccidia on digestion (amylolytic activity) in broiler chickens. Exp Parasitol. 1978; 45(2):234-40. DOI: 10.1016/0014-4894(78)90064-4. View

Alizadeh M, Rodriguez-Lecompte J, Yitbarek A, Sharif S, Crow G, Slominski B . Effect of yeast-derived products on systemic innate immune response of broiler chickens following a lipopolysaccharide challenge. Poult Sci. 2016; 95(10):2266-73. DOI: 10.3382/ps/pew154. View

Munyaka P, Echeverry H, Yitbarek A, Camelo-Jaimes G, Sharif S, Guenter W . Local and systemic innate immunity in broiler chickens supplemented with yeast-derived carbohydrates. Poult Sci. 2012; 91(9):2164-72. DOI: 10.3382/ps.2012-02306. View

Tini M, Jewell U, Camenisch G, Chilov D, Gassmann M . Generation and application of chicken egg-yolk antibodies. Comp Biochem Physiol A Mol Integr Physiol. 2002; 131(3):569-74. DOI: 10.1016/s1095-6433(01)00508-6. View

Alizadeh M, Munyaka P, Yitbarek A, Echeverry H, Rodriguez-Lecompte J . Maternal antibody decay and antibody-mediated immune responses in chicken pullets fed prebiotics and synbiotics. Poult Sci. 2016; 96(1):58-64. DOI: 10.3382/ps/pew244. View

Yitbarek A, Rodriguez-Lecompte J, Echeverry H, Munyaka P, Barjesteh N, Sharif S . Performance, histomorphology, and toll-like receptor, chemokine, and cytokine profile locally and systemically in broiler chickens fed diets supplemented with yeast-derived macromolecules. Poult Sci. 2013; 92(9):2299-310. DOI: 10.3382/ps.2013-03141. View

10.

Hamal K, Burgess S, Pevzner I, Erf G . Maternal antibody transfer from dams to their egg yolks, egg whites, and chicks in meat lines of chickens. Poult Sci. 2006; 85(8):1364-72. DOI: 10.1093/ps/85.8.1364. View

11.

Geyra A, Uni Z, Sklan D . Enterocyte dynamics and mucosal development in the posthatch chick. Poult Sci. 2001; 80(6):776-82. DOI: 10.1093/ps/80.6.776. View

12.

Pimentel J, Cook M . Improved growth in the progeny of hens immunized with jackbean urease. Poult Sci. 1988; 67(3):434-9. DOI: 10.3382/ps.0670434. View

13.

Chapman H . Milestones in avian coccidiosis research: a review. Poult Sci. 2014; 93(3):501-11. DOI: 10.3382/ps.2013-03634. View

14.

Klasing K . Nutrition and the immune system. Br Poult Sci. 2007; 48(5):525-37. DOI: 10.1080/00071660701671336. View

15.

Chapman H . A landmark contribution to poultry science--prophylactic control of coccidiosis in poultry. Poult Sci. 2009; 88(4):813-5. DOI: 10.3382/ps.2008-00316. View

16.

Murdoch B, Murdoch G, Greenwood S, McKay S . Nutritional Influence on Epigenetic Marks and Effect on Livestock Production. Front Genet. 2016; 7:182. PMC: 5075561. DOI: 10.3389/fgene.2016.00182. View

17.

Uni Z, Noy Y, Sklan D . Posthatch development of small intestinal function in the poult. Poult Sci. 1999; 78(2):215-22. DOI: 10.1093/ps/78.2.215. View

18.

Kim E, Leung H, Akhtar N, Li J, Barta J, Wang Y . Growth performance and gastrointestinal responses of broiler chickens fed corn-soybean meal diet without or with exogenous epidermal growth factor upon challenge with Eimeria. Poult Sci. 2017; 96(10):3676-3686. PMC: 5850350. DOI: 10.3382/ps/pex192. View

19.

Jensen G, Patterson K, Yoon I . Yeast culture has anti-inflammatory effects and specifically activates NK cells. Comp Immunol Microbiol Infect Dis. 2007; 31(6):487-500. DOI: 10.1016/j.cimid.2007.08.005. View

20.

Huyghebaert G, Ducatelle R, Van Immerseel F . An update on alternatives to antimicrobial growth promoters for broilers. Vet J. 2010; 187(2):182-8. DOI: 10.1016/j.tvjl.2010.03.003. View