» Articles » PMID: 31474791

Predictors and Colonoscopy Outcomes of Inadequate Bowel Cleansing: a 10-year Experience in 28,725 Patients

Overview
Specialty Gastroenterology
Date 2019 Sep 3
PMID 31474791
Citations 12
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Inadequate bowel preparation is still the main obstacle to a complete colonoscopy in many patients and necessitates many repeated procedures. We aimed to identify risk factors associated with inadequate bowel preparation and to better characterize these patients.

Methods: This was a retrospective study that reviewed electronic reports of colonoscopy procedures over a 10-year period. Patients were divided into 2 groups: adequate vs. non-adequate bowel preparation. A multivariate analysis was performed to identify variables associated with inadequate bowel preparation, including age, sex, setting (inpatient/outpatient), preparation regimen and procedures' indications. We examined the effect of inadequate preparation on colonoscopy quality indicators.

Results: Of the 28,725 patients included in the study, 6,702 (23.3%) had inadequate bowel preparation. In the multivariate analysis, advanced age (odds ratio [OR] 1.015, 95% confidence interval [CI] 1.013-1.017; P<0.01), male sex (OR 1.353, 95%CI 1.286-1.423; P<0.01) and a minority population (OR 1.635, 95%CI 1.531-1.746; P<0.01) were significantly associated with inadequate bowel preparation. The inpatient setting was among the most prominent factors associated with inadequate bowel preparation (OR 2.018, 95%CI 1.884-2.163; P<0.01). Adequate bowel preparation was associated with a higher polyp detection rate (26.8% vs. 23.6%; OR 1.22, 95%CI 1.109-1.347; P<0.01) and colorectal cancer (2.8% vs. 2.4%; OR 1.402, 95%CI 1.146-1.716; P<0.01), and higher frequencies of cecal (96.4% vs. 73.5%; OR 2.243, 95%CI 2.095-2.403; P<0.01) and terminal ileum intubation (8.1% vs. 5.4%; OR 1.243, 95%CI 1.088-1.434; P<0.01).

Conclusion: We outlined various factors associated with inadequate bowel preparation and confirmed its adverse effect on colonoscopy quality indicators.

Citing Articles

Text Message System for the Prediction of Colonoscopy Bowel Preparation Adequacy Before Colonoscopy: An Artificial Intelligence Image Classification Algorithm Based on Images of Stool Output.

Ramprasad C, Saini D, Del Carmen H, Krasnovsky L, Chandra R, McGregor R Gastro Hep Adv. 2025; 4(2):100556.

PMID: 39866713 PMC: 11760837. DOI: 10.1016/j.gastha.2024.09.011.


Performance of Computer-Aided Detection and Quality of Bowel Preparation: A Comprehensive Analysis of Colonoscopy Outcomes.

Norwood D, Thakkar S, Cartee A, Sarkis F, Torres-Herman T, Montalvan-Sanchez E Dig Dis Sci. 2024; 69(10):3681-3689.

PMID: 39285090 PMC: 11489221. DOI: 10.1007/s10620-024-08610-7.


Efficacy, tolerability, and safety of oral sulfate tablet versus 2 L-polyethylene glycol/ascorbate for bowel preparation in older patients: prospective, multicenter, investigator single-blinded, randomized study.

Kang H, Na S, Yoon J, Jung Y, Seo G, Cha J J Gastroenterol. 2024; 59(5):402-410.

PMID: 38492010 DOI: 10.1007/s00535-024-02089-9.


Establishment of a risk prediction model for bowel preparation failure prior to colonoscopy.

Zhang N, Xu M, Chen X BMC Cancer. 2024; 24(1):341.

PMID: 38486227 PMC: 10938670. DOI: 10.1186/s12885-024-12081-4.


Comparison of a novel mini-oral sulfate tablet and the conventional oral sulfate tablet in bowel preparation for colonoscopy: a prospective, randomized, investigator-blinded, multicenter, non-inferior, phase 3 trial.

Jeon S, Park S, Yang D, Cha J J Gastroenterol. 2023; 58(11):1114-1123.

PMID: 37542674 DOI: 10.1007/s00535-023-02023-5.


References
1.
Young C, Simpson R, King D, Lubowski D . Oral sodium phosphate solution is a superior colonoscopy preparation to polyethylene glycol with bisacodyl. Dis Colon Rectum. 2000; 43(11):1568-71. DOI: 10.1007/BF02236740. View

2.
Taylor C, Schubert M . Decreased efficacy of polyethylene glycol lavage solution (golytely) in the preparation of diabetic patients for outpatient colonoscopy: a prospective and blinded study. Am J Gastroenterol. 2001; 96(3):710-4. DOI: 10.1111/j.1572-0241.2001.03610.x. View

3.
Ness R, Manam R, Hoen H, Chalasani N . Predictors of inadequate bowel preparation for colonoscopy. Am J Gastroenterol. 2001; 96(6):1797-802. DOI: 10.1111/j.1572-0241.2001.03874.x. View

4.
Rex D, Imperiale T, Latinovich D, Bratcher L . Impact of bowel preparation on efficiency and cost of colonoscopy. Am J Gastroenterol. 2002; 97(7):1696-700. DOI: 10.1111/j.1572-0241.2002.05827.x. View

5.
Harewood G, Sharma V, de Garmo P . Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc. 2003; 58(1):76-9. DOI: 10.1067/mge.2003.294. View