» Articles » PMID: 31440717

Persistent Type IV Hypersensitivity After Cyanoacrylate Closure of the Great Saphenous Vein

Overview
Date 2019 Aug 24
PMID 31440717
Citations 8
Authors
Affiliations
Soon will be listed here.
Abstract

The VenaSeal (Medtronic, Minneapolis, Minn) cyanoacrylate closure system is a nonthermal technique for ablating saphenous veins using a proprietary -butyl cyanoacrylate. One possible side effect is an allergic reaction to cyanoacrylate. We report the case of a 49-year-old woman treated with cyanoacrylate closure who developed a persistent type IV hypersensitivity reaction. The patient elected to have the vein excised, and the histologic features were consistent with a type IV hypersensitivity reaction.

Citing Articles

thrombophlebitis complicating cyanoacrylate closure procedure.

Barranco-Trabi J, Desai K, Chen D, Kellicut D, Brandon W, Chi S J Vasc Surg Cases Innov Tech. 2024; 10(6):101454.

PMID: 39296372 PMC: 11408044. DOI: 10.1016/j.jvscit.2024.101454.


Ethical Considerations and Adverse Events in Cyanoacrylate Embolization for Non-Saphenous Veins: A Case Report.

Park I Vasc Specialist Int. 2024; 40:6.

PMID: 38433505 PMC: 10910212. DOI: 10.5758/vsi.230102.


Severe adverse reactions after cyanoacrylate endovenous ablation.

Louden C, Clark J, Yanquez F, Labropoulos N, DiMaggio P, R Leon Jr L J Vasc Surg Cases Innov Tech. 2023; 9(4):101309.

PMID: 37767344 PMC: 10520435. DOI: 10.1016/j.jvscit.2023.101309.


Complex Hypersensitivity and Irritation Reaction (CHAIR) Phenomenon after Cyanoacrylate Closure of Varicose Vein.

Joh J, Joo S Vasc Specialist Int. 2023; 39:27.

PMID: 37748929 PMC: 10519939. DOI: 10.5758/vsi.230062.


Septicemia after cyanoacrylate glue closure of varicose veins.

Nishizawa M, Kudo T J Vasc Surg Cases Innov Tech. 2022; 8(4):653-656.

PMID: 36262917 PMC: 9574572. DOI: 10.1016/j.jvscit.2022.09.008.


References
1.
Toriumi D, Bagal A . Cyanoacrylate tissue adhesives for skin closure in the outpatient setting. Otolaryngol Clin North Am. 2002; 35(1):103-18, vi-vii. DOI: 10.1016/s0030-6665(03)00097-5. View

2.
Wang Y, Cheng L, Li N . Histopathological study of vascular changes after intra-arterial and intravenous injection of N-butyl-2-cyanoacrylate. Chin J Dig Dis. 2006; 7(3):175-9. DOI: 10.1111/j.1443-9573.2006.00264.x. View

3.
Proebstle T, Alm J, Gockeritz O, Wenzel C, Noppeney T, Lebard C . Three-year European follow-up of endovenous radiofrequency-powered segmental thermal ablation of the great saphenous vein with or without treatment of calf varicosities. J Vasc Surg. 2011; 54(1):146-52. DOI: 10.1016/j.jvs.2010.12.051. View

4.
Almeida J, Min R, Raabe R, McLean D, Madsen M . Cyanoacrylate adhesive for the closure of truncal veins: 60-day swine model results. Vasc Endovascular Surg. 2011; 45(7):631-5. DOI: 10.1177/1538574411413938. View

5.
Min R, Almeida J, McLean D, Madsen M, Raabe R . Novel vein closure procedure using a proprietary cyanoacrylate adhesive: 30-day swine model results. Phlebology. 2012; 27(8):398-403. DOI: 10.1258/phleb.2011.011084. View