Angioimmunoblastic Lymphadenopathy with Dysproteinemia. A Pathogenetic Link Between Lymphoid Proliferation and Malignant Lymphoma

Overview

Journal Am J Med

Specialty General Medicine

Date 1979 Sep 1

PMID 314238

Citations 8

Authors

A Z Bluming

H G Cohen

A Saxon

Affiliations

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Abstract

Two patients with angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) were studied. Both patients had marked increases in all three major immunoglobulin classes, and both lacked suppressor cell activity in vitro. These findings are consistent with the theory that AILD is a defectively regulated immune response to an unidentified antigen(s) and could provide clues to the pathogenesis of other lymphoproliferative disorders as well.

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Lymphoproliferations in the bone marrow: identification and evolution, classification and staging.

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Evidence for monoclonal T lymphocyte proliferation in angioimmunoblastic lymphadenopathy.

OConnor N, Crick J, Wainscoat J, Gatter K, STEIN H, Falini B J Clin Pathol. 1986; 39(11):1229-32.

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