Article: Zinc source modulates zootechnical characteristics, intestinal features, humoral response, and paraoxonase (PON1) activity in broilers

The current experiment was performed to find the potential effect of inorganic and organic forms of zinc (Zn) on growth, intestinal histomorphology, immune response, and paraoxonase (PON1) activity in broiler. In this experiment, a total of 450 broiler chickens were assigned to four experimental and control groups. The birds received organic Zn at the rate of 50 mg/kg (OZ-50) and 60 mg/kg (OZ-60) or inorganic Zn at the rate of 50 mg/kg (IZ-50) and 60 mg/kg (IZ-60) for an experimental period of 30 days. Significantly (P < 0.05) higher feed consumption, body weight, feed conversion ratio, and production efficiency factor (PEF) were recorded in OZ-50. Similarly, antibody titer against infectious bronchitis (IB) and PON1 activity was higher (P < 0.05) in OZ-50 compared with the control group. In addition, significantly (P < 0.05) higher villus dimensions and goblet cell count were recorded for the group OZ-50 compared with other treatments. It was concluded that the organic form of Zn was superior in improving the growth, histological features of intestines, humoral response, and PON1 activity in broiler.

Citing Articles

Synergistic Effects of Hydroxychloride and Organic Zinc on Performance, Carcass Characteristics, Liver and Tibia Mineral Profiles of Broiler Chickens.

Sadr V, Nguyen H, Pineda L, Han Y, Toghyani M Biol Trace Elem Res. 2024; .

PMID: 39312126 DOI: 10.1007/s12011-024-04385-0.

Determining the optimal level and the effect of different zinc sources on performance, egg quality and the immune system of laying hens at the end of the production period.

Alirezaei Shahraki P, Kheiri F, Amanlou H, Faghani M, Jalali S Vet Med Sci. 2024; 10(5):e70035.

PMID: 39258517 PMC: 11388059. DOI: 10.1002/vms3.70035.

Effects of zinc supplementation from organic and inorganic sources on growth, blood biochemical indices, and intestinal microarchitecture in broilers.

Khan M, Chand N, Naz S, Alonaizan R, Hu H, Shamsi S Vet Q. 2024; 44(1):1-7.

PMID: 38295836 PMC: 10836478. DOI: 10.1080/01652176.2023.2298491.

Dietary trace mineral pattern influences gut microbiota and intestinal health of broilers.

Wang C, Wang L, Chen Q, Guo X, Zhang L, Liao X J Anim Sci. 2023; 101.

PMID: 37439267 PMC: 10370895. DOI: 10.1093/jas/skad240.

Nano Zinc Oxide Improves Performance, IGF-I mRNA Expression, Meat Quality, and Humeral Immune Response and Alleviates Oxidative Stress and NF-κB Immunohistochemistry of Broiler Chickens.

Alian H, Samy H, Ibrahim M, Yusuf M, Mahmoud M Biol Trace Elem Res. 2022; 201(8):4062-4078.

PMID: 36434422 PMC: 10279576. DOI: 10.1007/s12011-022-03494-y.

References

1.

Jahanian R, Rasouli E . Effects of dietary substitution of zinc-methionine for inorganic zinc sources on growth performance, tissue zinc accumulation and some blood parameters in broiler chicks. J Anim Physiol Anim Nutr (Berl). 2014; 99(1):50-58. DOI: 10.1111/jpn.12213. View

2.

Shah M, Zaneb H, Masood S, Khan R, Ashraf S, Sikandar A . Effect of Dietary Supplementation of Zinc and Multi-Microbe Probiotic on Growth Traits and Alteration of Intestinal Architecture in Broiler. Probiotics Antimicrob Proteins. 2018; 11(3):931-937. DOI: 10.1007/s12602-018-9424-9. View

3.

Chand N, Muhammad S, Khan R, Alhidary I, Rehman Z . Ameliorative effect of synthetic γ-aminobutyric acid (GABA) on performance traits, antioxidant status and immune response in broiler exposed to cyclic heat stress. Environ Sci Pollut Res Int. 2016; 23(23):23930-23935. DOI: 10.1007/s11356-016-7604-2. View

4.

Payne R, Bidner T, Fakler T, Southern L . Growth and intestinal morphology of pigs from sows fed two zinc sources during gestation and lactation. J Anim Sci. 2006; 84(8):2141-9. DOI: 10.2527/jas.2005-627. View

5.

Star L, Van der Klis J, Rapp C, Ward T . Bioavailability of organic and inorganic zinc sources in male broilers. Poult Sci. 2012; 91(12):3115-20. DOI: 10.3382/ps.2012-02314. View

6.

Rehman Z, Chand N, Khan R . The effect of vitamin E, L-carnitine, and ginger on production traits, immune response, and antioxidant status in two broiler strains exposed to chronic heat stress. Environ Sci Pollut Res Int. 2017; 24(34):26851-26857. DOI: 10.1007/s11356-017-0304-8. View

7.

Min Y, Liu F, Qi X, Ji S, Cui L, Wang Z . Effects of organic zinc on tibia quality, mineral deposit, and metallothionein expression level of aged hens. Poult Sci. 2018; 98(1):366-372. PMC: 6347128. DOI: 10.3382/ps/pey386. View

8.

Hu C, Qian Z, Song J, Luan Z, Zuo A . Effects of zinc oxide-montmorillonite hybrid on growth performance, intestinal structure, and function of broiler chicken. Poult Sci. 2012; 92(1):143-50. DOI: 10.3382/ps.2012-02250. View

9.

Jarosz L, Marek A, Gradzki Z, Kwiecien M, Zylinska B, Kaczmarek B . Effect of feed supplementation with zinc glycine chelate and zinc sulfate on cytokine and immunoglobulin gene expression profiles in chicken intestinal tissue. Poult Sci. 2017; 96(12):4224-4235. DOI: 10.3382/ps/pex253. View

10.

Rahman H, Qureshi M, Khan R . Influence of dietary zinc on semen traits and seminal plasma antioxidant enzymes and trace minerals of beetal bucks. Reprod Domest Anim. 2014; 49(6):1004-7. DOI: 10.1111/rda.12422. View

Zinc Source Modulates Zootechnical Characteristics, Intestinal Features, Humoral Response, and Paraoxonase (PON1) Activity in Broilers