Complement System and Age-related Macular Degeneration: Drugs and Challenges

Overview

Journal Drug Des Devel Ther

Specialty Pharmacology

Date 2019 Aug 15

PMID 31409975

Citations 40

Authors

Jiali Wu

Xiaodong Sun

Affiliations

Soon will be listed here.

Abstract

Age-related macular degeneration (AMD) is directly attributable to vision loss, posing significant pressure on public health. AMD is recognized to be a multi-factorial disease and among them, complement system is under heated discussion in recent years. In this review, we start with an overview of complement pathways involved in AMD and their therapies correspondingly. Finally, we discuss the development of the therapeutics existed now. Also, we enclose a list of drugs undergoing clinical trials.

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