» Articles » PMID: 31405724

Automated Segmentation of Tissues Using CT and MRI: A Systematic Review

Abstract

Rationale And Objectives: The automated segmentation of organs and tissues throughout the body using computed tomography and magnetic resonance imaging has been rapidly increasing. Research into many medical conditions has benefited greatly from these approaches by allowing the development of more rapid and reproducible quantitative imaging markers. These markers have been used to help diagnose disease, determine prognosis, select patients for therapy, and follow responses to therapy. Because some of these tools are now transitioning from research environments to clinical practice, it is important for radiologists to become familiar with various methods used for automated segmentation.

Materials And Methods: The Radiology Research Alliance of the Association of University Radiologists convened an Automated Segmentation Task Force to conduct a systematic review of the peer-reviewed literature on this topic.

Results: The systematic review presented here includes 408 studies and discusses various approaches to automated segmentation using computed tomography and magnetic resonance imaging for neurologic, thoracic, abdominal, musculoskeletal, and breast imaging applications.

Conclusion: These insights should help prepare radiologists to better evaluate automated segmentation tools and apply them not only to research, but eventually to clinical practice.

Citing Articles

AI-Based 3D Liver Segmentation and Volumetric Analysis in Living Donor Data.

Mun S, Choi S, Kim Y, Kim K, Lee W J Imaging Inform Med. 2025; .

PMID: 40087225 DOI: 10.1007/s10278-025-01468-9.


A Case for Automated Segmentation of MRI Data in Milder Neurodegenerative Diseases.

Lewis C, Johnston J, DSouza P, Kolstad J, Zoppo C, Vardar Z medRxiv. 2025; .

PMID: 40034761 PMC: 11875249. DOI: 10.1101/2025.02.18.25322304.


In-House Fabrication and Validation of 3D-Printed Custom-Made Medical Devices for Planning and Simulation of Peripheral Endovascular Therapies.

Mersanne A, Foresti R, Martini C, Caffarra Malvezzi C, Rossi G, Fornasari A Diagnostics (Basel). 2025; 15(1.

PMID: 39795536 PMC: 11719810. DOI: 10.3390/diagnostics15010008.


Three-Dimensional Bone-Image Synthesis with Generative Adversarial Networks.

Angermann C, Bereiter-Payr J, Stock K, Degenhart G, Haltmeier M J Imaging. 2024; 10(12).

PMID: 39728215 PMC: 11678923. DOI: 10.3390/jimaging10120318.


Segmentation-Based Measurement of Orbital Structures: Achievements in Eyeball Volume Estimation and Barriers in Optic Nerve Analysis.

Lee Y, Kim H, Chung Y, Cho W, Park J, Paik J Diagnostics (Basel). 2024; 14(23).

PMID: 39682551 PMC: 11640721. DOI: 10.3390/diagnostics14232643.


References
1.
Han D, Shim H, Jeon B, Jang Y, Hong Y, Jung S . Automatic Coronary Artery Segmentation Using Active Search for Branches and Seemingly Disconnected Vessel Segments from Coronary CT Angiography. PLoS One. 2016; 11(8):e0156837. PMC: 4990346. DOI: 10.1371/journal.pone.0156837. View

2.
Akhondi-Asl A, Hoyte L, Lockhart M, Warfield S . A logarithmic opinion pool based STAPLE algorithm for the fusion of segmentations with associated reliability weights. IEEE Trans Med Imaging. 2014; 33(10):1997-2009. PMC: 4264575. DOI: 10.1109/TMI.2014.2329603. View

3.
Korfiatis P, Kline T, Erickson B . Automated Segmentation of Hyperintense Regions in FLAIR MRI Using Deep Learning. Tomography. 2017; 2(4):334-340. PMC: 5215737. DOI: 10.18383/j.tom.2016.00166. View

4.
Prados F, Cardoso M, Yiannakas M, Hoy L, Tebaldi E, Kearney H . Fully automated grey and white matter spinal cord segmentation. Sci Rep. 2016; 6:36151. PMC: 5082365. DOI: 10.1038/srep36151. View

5.
Alba X, Lekadir K, Pereanez M, Medrano-Gracia P, Young A, Frangi A . Automatic initialization and quality control of large-scale cardiac MRI segmentations. Med Image Anal. 2017; 43:129-141. DOI: 10.1016/j.media.2017.10.001. View