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Lower Limb Rigidity Is Associated with Frequent Falls in Parkinson's Disease

Overview
Publisher Wiley
Specialty Neurology
Date 2019 Aug 9
PMID 31392245
Citations 8
Authors
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Abstract

Background And Objective: The role of muscle rigidity as an etiological factor of falls in Parkinson's disease (PD) is poorly understood. Our objective was to determine whether lower leg rigidity was differentially associated with frequent falls in PD compared to upper limb, neck, and total rigidity measures.

Methods: We examined the associations between Unified Parkinson's Disease Rating Scale-Part III (motor) rigidity subscores and the history of monthly or more frequent falls in 216 individuals with PD (age, 66 ± 10 years; 36% female; disease duration, 7 ± 5 years) with logistic regression.

Results: A total of 35 individuals were frequent fallers. Significant associations were identified between lower limb rigidity and frequent falls ( = 0.01) after controlling for age, sex, PD duration, total Unified Parkinson's Disease Rating Scale- Part III score, and presence of freezing of gait. No significant associations ( ≥ 0.14) were identified for total, arm, or neck rigidity.

Conclusion: Lower limb rigidity is related to frequent falls in people with PD. Further investigation may be warranted into how parkinsonian rigidity could cause falls.

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References
1.
McKay J, Ting L, Hackney M . Balance, Body Motion, and Muscle Activity After High-Volume Short-Term Dance-Based Rehabilitation in Persons With Parkinson Disease: A Pilot Study. J Neurol Phys Ther. 2016; 40(4):257-68. PMC: 5025380. DOI: 10.1097/NPT.0000000000000150. View

2.
Tomlinson C, Stowe R, Patel S, Rick C, Gray R, Clarke C . Systematic review of levodopa dose equivalency reporting in Parkinson's disease. Mov Disord. 2010; 25(15):2649-53. DOI: 10.1002/mds.23429. View

3.
Gray P, Hildebrand K . Fall risk factors in Parkinson's disease. J Neurosci Nurs. 2000; 32(4):222-8. DOI: 10.1097/01376517-200008000-00006. View

4.
Bartolic A, Pirtosek Z, Rozman J, Ribaric S . Postural stability of Parkinson's disease patients is improved by decreasing rigidity. Eur J Neurol. 2005; 12(2):156-9. DOI: 10.1111/j.1468-1331.2004.00942.x. View

5.
Li F, Harmer P, Fitzgerald K, Eckstrom E, Stock R, Galver J . Tai chi and postural stability in patients with Parkinson's disease. N Engl J Med. 2012; 366(6):511-9. PMC: 3285459. DOI: 10.1056/NEJMoa1107911. View