» Articles » PMID: 31384725

Evidence of an Epigenetics System in Archaea

Overview
Date 2019 Aug 7
PMID 31384725
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

Changes in the phenotype of a cell or organism that are heritable but do not involve changes in DNA sequence are referred to as epigenetic. They occur primarily through the gain or loss of chemical modification of chromatin protein or DNA. Epigenetics is therefore a non-Mendelian process. The study of epigenetics in eukaryotes is expanding with advances in knowledge about the relationship between mechanism and phenotype and as a requirement for multicellularity and cancer. However, life also includes other groups or domains, notably the bacteria and archaea. The occurrence of epigenetics in these deep lineages is an emerging topic accompanied by controversy. In these non-eukaryotic organisms, epigenetics is critically important because it stimulates new evolutionary theory and refines perspective about biological action.

Citing Articles

Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health.

Aparecida Dos Santos France F, Maeda D, Rodrigues A, Ono M, Lopes Nogueira Marchetti F, Marchetti M Epigenetics. 2024; 19(1):2400423.

PMID: 39255363 PMC: 11404605. DOI: 10.1080/15592294.2024.2400423.


The Evolution of the Hallmarks of Aging.

Lemoine M Front Genet. 2021; 12:693071.

PMID: 34512720 PMC: 8427668. DOI: 10.3389/fgene.2021.693071.


Antibiotic-Resistant Bacteria in Aquaculture and Climate Change: A Challenge for Health in the Mediterranean Area.

Pepi M, Focardi S Int J Environ Res Public Health. 2021; 18(11).

PMID: 34073520 PMC: 8198758. DOI: 10.3390/ijerph18115723.

References
1.
Henderson I, Owen P, Nataro J . Molecular switches--the ON and OFF of bacterial phase variation. Mol Microbiol. 1999; 33(5):919-32. DOI: 10.1046/j.1365-2958.1999.01555.x. View

2.
Haagmans W, van der Woude M . Phase variation of Ag43 in Escherichia coli: Dam-dependent methylation abrogates OxyR binding and OxyR-mediated repression of transcription. Mol Microbiol. 2000; 35(4):877-87. DOI: 10.1046/j.1365-2958.2000.01762.x. View

3.
Jorgensen H, Bird A . MeCP2 and other methyl-CpG binding proteins. Ment Retard Dev Disabil Res Rev. 2002; 8(2):87-93. DOI: 10.1002/mrdd.10021. View

4.
Forbes A, Patrie S, Taylor G, Kim Y, Jiang L, Kelleher N . Targeted analysis and discovery of posttranslational modifications in proteins from methanogenic archaea by top-down MS. Proc Natl Acad Sci U S A. 2004; 101(9):2678-83. PMC: 365680. DOI: 10.1073/pnas.0306575101. View

5.
Banerjee S, Chowdhury R . An orphan DNA (cytosine-5-)-methyltransferase in Vibrio cholerae. Microbiology (Reading). 2006; 152(Pt 4):1055-1062. DOI: 10.1099/mic.0.28624-0. View