Solvent Demulsification-dispersive Liquid-liquid Microextraction Based on Solidification of Floating Organic Drop Coupled with Ultra-high-performance Liquid Chromatography-tandem Mass Spectrometry for Simultaneous Determination of 13 Organophosphate...

Overview

Journal Sci Rep

Specialty Science

Date 2019 Aug 7

PMID 31383918

Citations 4

Authors

Qing Luo

Shiyu Wang

Muhammad Adeel

Yue Shan

Hui Wang

Li-Na Sun

Affiliations

Soon will be listed here.

Abstract

This study developed a novel method for the determination of 13 organophosphate esters (OPEs) in aqueous samples through the optimization of solvent demulsification-dispersive liquid-liquid microextraction based on solidification of floating organic drop procedure coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry. The proposed method was rapid and accurate and could be used in field applications. Under the most suitable conditions, the limit of detection and limit of quantification ranged from 0.16 ng/L to 20.0 ng/L and from 0.55 ng/L to 66.7 ng/L, respectively. The enrichment factors (EFs) ranged from 30 to 46. The relative standard deviations were less than 15%. The spiked recoveries ranged between 68.2% and 97.7% in the analysis of actual aqueous samples. The proposed method was convenient, environment friendly, and time and solvent saving and could be used in field applications compared with other methods. Various concentrations and types of OPEs were detected in tap water, river water, and effluent of sewage treatment plant. Effluent samples had the highest detected levels and types of OPEs.

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References

Jin T, Cheng J, Cai C, Cheng M, Wu S, Zhou H . Graphene oxide based sol-gel stainless steel fiber for the headspace solid-phase microextraction of organophosphate ester flame retardants in water samples. J Chromatogr A. 2016; 1457:1-6. DOI: 10.1016/j.chroma.2016.06.038. View

Tsao Y, Wang Y, Wu S, Ding W . Microwave-assisted headspace solid-phase microextraction for the rapid determination of organophosphate esters in aqueous samples by gas chromatography-mass spectrometry. Talanta. 2011; 84(2):406-10. DOI: 10.1016/j.talanta.2011.01.055. View

Brommer S, Harrad S, Van den Eede N, Covaci A . Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples. J Environ Monit. 2012; 14(9):2482-7. DOI: 10.1039/c2em30303e. View

Quintana J, Rodil R, Lopez-Mahia P, Muniategui-Lorenzo S, Prada-Rodriguez D . Optimisation of a selective method for the determination of organophosphorous triesters in outdoor particulate samples by pressurised liquid extraction and large-volume injection gas chromatography-positive chemical ionisation-tandem mass.... Anal Bioanal Chem. 2007; 388(5-6):1283-93. DOI: 10.1007/s00216-007-1338-4. View

Salamova A, Hermanson M, Hites R . Organophosphate and halogenated flame retardants in atmospheric particles from a European Arctic site. Environ Sci Technol. 2014; 48(11):6133-40. DOI: 10.1021/es500911d. View

OBrien J, Thai P, Brandsma S, Leonards P, Ort C, Mueller J . Wastewater analysis of Census day samples to investigate per capita input of organophosphorus flame retardants and plasticizers into wastewater. Chemosphere. 2015; 138:328-34. DOI: 10.1016/j.chemosphere.2015.06.014. View

Wang R, Tang J, Xie Z, Mi W, Chen Y, Wolschke H . Occurrence and spatial distribution of organophosphate ester flame retardants and plasticizers in 40 rivers draining into the Bohai Sea, north China. Environ Pollut. 2015; 198:172-8. DOI: 10.1016/j.envpol.2014.12.037. View

Zhang Q, Ji C, Yin X, Yan L, Lu M, Zhao M . Thyroid hormone-disrupting activity and ecological risk assessment of phosphorus-containing flame retardants by in vitro, in vivo and in silico approaches. Environ Pollut. 2015; 210:27-33. DOI: 10.1016/j.envpol.2015.11.051. View

Matuszewski B, Constanzer M, Chavez-Eng C . Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem. 2003; 75(13):3019-30. DOI: 10.1021/ac020361s. View

10.

Cristale J, Katsoyiannis A, Sweetman A, Jones K, Lacorte S . Occurrence and risk assessment of organophosphorus and brominated flame retardants in the River Aire (UK). Environ Pollut. 2013; 179:194-200. DOI: 10.1016/j.envpol.2013.04.001. View

11.

Tan X, Luo X, Zheng X, Li Z, Sun R, Mai B . Distribution of organophosphorus flame retardants in sediments from the Pearl River Delta in South China. Sci Total Environ. 2015; 544:77-84. DOI: 10.1016/j.scitotenv.2015.11.089. View

12.

Makinen M, Makinen M, Koistinen J, Pasanen A, Pasanen P, Kalliokoski P . Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments. Environ Sci Technol. 2009; 43(3):941-7. DOI: 10.1021/es802593t. View

13.

Ding J, Shen X, Liu W, Covaci A, Yang F . Occurrence and risk assessment of organophosphate esters in drinking water from Eastern China. Sci Total Environ. 2015; 538:959-65. DOI: 10.1016/j.scitotenv.2015.08.101. View

14.

Luo Q, Shan Y, Muhammad A, Wang S, Sun L, Wang H . Levels, distribution, and sources of organophosphate flame retardants and plasticizers in urban soils of Shenyang, China. Environ Sci Pollut Res Int. 2018; 25(31):31752-31761. DOI: 10.1007/s11356-018-3156-y. View

15.

Yang F, Ding J, Huang W, Xie W, Liu W . Particle size-specific distributions and preliminary exposure assessments of organophosphate flame retardants in office air particulate matter. Environ Sci Technol. 2013; 48(1):63-70. DOI: 10.1021/es403186z. View

16.

He C, Zheng J, Qiao L, Chen S, Yang J, Yuan J . Occurrence of organophosphorus flame retardants in indoor dust in multiple microenvironments of southern China and implications for human exposure. Chemosphere. 2015; 133:47-52. DOI: 10.1016/j.chemosphere.2015.03.043. View

17.

Garcia M, Rodriguez I, Cela R . Microwave-assisted extraction of organophosphate flame retardants and plasticizers from indoor dust samples. J Chromatogr A. 2006; 1152(1-2):280-6. DOI: 10.1016/j.chroma.2006.11.046. View

18.

Castro-Jimenez J, Berrojalbiz N, Pizarro M, Dachs J . Organophosphate ester (OPE) flame retardants and plasticizers in the open Mediterranean and Black Seas atmosphere. Environ Sci Technol. 2014; 48(6):3203-9. DOI: 10.1021/es405337g. View

19.

Luo H, Xian Y, Guo X, Luo D, Wu Y, Lu Y . Dispersive liquid-liquid microextraction combined with ultrahigh performance liquid chromatography/tandem mass spectrometry for determination of organophosphate esters in aqueous samples. ScientificWorldJournal. 2014; 2014:162465. PMC: 3927578. DOI: 10.1155/2014/162465. View

20.

Castro-Jimenez J, Gonzalez-Gaya B, Pizarro M, Casal P, Pizarro-Alvarez C, Dachs J . Organophosphate Ester Flame Retardants and Plasticizers in the Global Oceanic Atmosphere. Environ Sci Technol. 2016; 50(23):12831-12839. DOI: 10.1021/acs.est.6b04344. View