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Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience

Overview
Journal Open Forum Infect Dis
Specialty Infectious Diseases
Date 2019 Aug 4
PMID 31375834
Citations 61
Authors
Jenna Rossoff
Sonali Chaudhury
Maulin Soneji
Sameer J Patel
Soyang Kwon
Amy Armstrong
William J Muller
Affiliations
Soon will be listed here.
Abstract

Pediatric patients frequently present with illnesses strongly suggesting infection, but without a clearly identified etiology. Our center has recently added a commercially available plasma metagenomic sequencing assay to its available diagnostic testing. Our experience with the first 100 tests suggests that this technology has good clinical performance with >90% sensitivity.

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