Dataset for the Spore Surface Proteome and Hydrophobin A/RodA Proteoforms of A.flavus

Overview

Journal Data Brief

Date 2019 Aug 3

PMID 31372461

Citations 3

Authors

Mohammed Razeeth Shait Mohammed

Muthu Kumar Balamurgan

Rabbind Singh Amrathlal

Priyadharshini Kannan

Jeya Maheshwari Jayapal

Venkatesh Prajna Namperumalsamy

Lalitha Prajna

Kuppamuthu Dharmalingam

Affiliations

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Abstract

Fungal keratitis is a major sight-threatening corneal infection: and mycotic keratitis is more common in tropical parts of the world including India. and are the predominant causative agents of corneal infection. We extracted conidial surface proteins of from saprophyte and clinical isolates and analyzed the proteins using high resolution mass spectrometry. The data revealed ecotype specific alteration in surface proteome since the proteome profile of the clinical isolates and saprophyte showed significant differences. Detailed examination of the mass spec data of RodA proteins extracted from polyacrylamide gels revealed the presence of two proteoforms of this protein. We also identified the mechanism of formation of these two isoforms. Detailed analysis of this data and the conclusions derived are described in the article, "Identification of the proteoforms of surface localized Rod A of and determination of the mechanism of proteoform generation" [1].

Citing Articles

Melanin depletion affects Aspergillus flavus conidial surface proteins, architecture, and virulence.

Rudhra O, Gnanam H, Sivaperumal S, Namperumalsamy V, Prajna L, Kuppamuthu D Appl Microbiol Biotechnol. 2024; 108(1):291.

PMID: 38592509 PMC: 11004046. DOI: 10.1007/s00253-024-13107-4.

Hydrophobins: Physicochemical Properties, Biochemical Properties, and Functions in Solid Polymer Degradation.

Tanaka T, Terauchi Y, Yoshimi A, Abe K Microorganisms. 2022; 10(8).

PMID: 35893556 PMC: 9394342. DOI: 10.3390/microorganisms10081498.

Local Activation of the Alternative Pathway of Complement System in Mycotic Keratitis Patient Tear.

Razeeth Shait Mohammed M, Krishnan S, Amrathlal R, Jayapal J, Namperumalsamy V, Prajna L Front Cell Infect Microbiol. 2020; 10:205.

PMID: 32435625 PMC: 7218074. DOI: 10.3389/fcimb.2020.00205.

References

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Kandhavelu J, Demonte N, Namperumalsamy V, Prajna L, Thangavel C, Jayapal J . Aspergillus flavus induced alterations in tear protein profile reveal pathogen-induced host response to fungal infection. J Proteomics. 2016; 152:13-21. DOI: 10.1016/j.jprot.2016.10.009. View

Razeeth Shait Mohammed M, Balamurugan M, Amrathlal R, Kannan P, Jayapal J, Namperumalsamy V . Identification of the proteoforms of surface localized Rod A of Aspergillus flavus and determination of the mechanism of proteoform generation. J Proteomics. 2018; 193:62-70. DOI: 10.1016/j.jprot.2018.12.016. View