Clinical and Histological Comparison of Platelet-rich Fibrin Versus Non-eugenol Periodontal Dressing in the Treatment of Gingival Hyperpigmentation

Overview

Journal J Indian Soc Periodontol

Date 2019 Aug 2

PMID 31367132

Citations 6

Authors

Ritu Dahiya

Anshu Blaggana

Vinod Panwar

Shubham Kumar

Abhinav Kathuria

Srijna Malik

Affiliations

Soon will be listed here.

Abstract

Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery.

Materials And Methods: A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3 and 5 day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5 day.

Results: On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group.

Conclusion: PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.

Citing Articles

Comparison of glued platelet-rich fibrin membrane and noneugenol pack as periodontal dressings after gingival depigmentation.

Poojari M, Shah M, Nadig P J Indian Soc Periodontol. 2025; 28(3):376-379.

PMID: 39742063 PMC: 11684567. DOI: 10.4103/jisp.jisp_270_23.

Clinical and Patient-Reported Outcome Measures of Palatal Donor Site Healing Using Polyvinylpyrrolidone-Sodium Hyaluronate Gel as a Dressing Material Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial.

Baroudi M, Othman M Clin Exp Dent Res. 2024; 10(6):e70026.

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From Healing to Regeneration: A Comprehensive Review of the Efficacy of Platelet-Rich Fibrin in Periodontal Plastic Surgery Procedures.

Jamjoom A Cureus. 2024; 16(9):e69287.

PMID: 39268023 PMC: 11392565. DOI: 10.7759/cureus.69287.

Injectable platelet rich fibrin effect on laser depigmented gingiva: a clinical randomized controlled split mouth trial with histological assessment.

Ibrahim S, Mandil I, Ezzatt O J Appl Oral Sci. 2024; 32:e20230307.

PMID: 38536994 PMC: 11018297. DOI: 10.1590/1678-7757-2022-0307.

Comparative analysis of platelet-rich fibrin membrane and 0.2% hyaluronic acid gel on healing following gingival depigmentation procedure.

Kale A, Sethi K, Mahale S, Karde P, Kale L, Choudhary S J Indian Soc Periodontol. 2024; 27(6):636-641.

PMID: 38434500 PMC: 10906787. DOI: 10.4103/jisp.jisp_291_22.

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