Sequence Variation at the MTHFD1L-AKAP12 and FOPNL Loci Does Not Influence Multiple Myeloma Survival in Sweden

Overview

Journal Blood Cancer J

Date 2019 Aug 1

PMID 31363079

Authors

Mina Ali

Konstantinos Lemonakis

Anna-Karin Wihlborg

Ljupco Veskovski

Ingemar Turesson

Ulf-Henrik Mellqvist

Urban Gullberg

Markus Hansson

Bjorn Nilsson

Affiliations

Soon will be listed here.

References

Kyle R, Therneau T, Rajkumar S, Larson D, Plevak M, Offord J . Prevalence of monoclonal gammopathy of undetermined significance. N Engl J Med. 2006; 354(13):1362-9. DOI: 10.1056/NEJMoa054494. View

Sedjai F, Acquaviva C, Chevrier V, Chauvin J, Coppin E, Aouane A . Control of ciliogenesis by FOR20, a novel centrosome and pericentriolar satellite protein. J Cell Sci. 2010; 123(Pt 14):2391-401. DOI: 10.1242/jcs.065045. View

Chubb D, Weinhold N, Broderick P, Chen B, Johnson D, Forsti A . Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. Nat Genet. 2013; 45(10):1221-1225. PMC: 5053356. DOI: 10.1038/ng.2733. View

Weinhold N, Johnson D, Chubb D, Chen B, Forsti A, Hosking F . The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. Nat Genet. 2013; 45(5):522-525. PMC: 5056630. DOI: 10.1038/ng.2583. View

Su B, Bu Y, Engelberg D, Gelman I . SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway. J Biol Chem. 2009; 285(7):4578-86. PMC: 2836062. DOI: 10.1074/jbc.M109.073494. View

Latouche A, Porcher R, Chevret S . Sample size formula for proportional hazards modelling of competing risks. Stat Med. 2004; 23(21):3263-74. DOI: 10.1002/sim.1915. View

Rajkumar S, Dimopoulos M, Palumbo A, Blade J, Merlini G, Mateos M . International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014; 15(12):e538-48. DOI: 10.1016/S1470-2045(14)70442-5. View

Weiss B, Abadie J, Verma P, Howard R, Kuehl W . A monoclonal gammopathy precedes multiple myeloma in most patients. Blood. 2009; 113(22):5418-22. PMC: 2689043. DOI: 10.1182/blood-2008-12-195008. View

Broderick P, Chubb D, Johnson D, Weinhold N, Forsti A, Lloyd A . Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk. Nat Genet. 2011; 44(1):58-61. PMC: 5108406. DOI: 10.1038/ng.993. View

10.

Schoenfeld D . Sample-size formula for the proportional-hazards regression model. Biometrics. 1983; 39(2):499-503. View

11.

Johnson D, Weinhold N, Mitchell J, Chen B, Kaiser M, Begum D . Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma. Nat Commun. 2016; 7:10290. PMC: 4729868. DOI: 10.1038/ncomms10290. View

12.

Auton A, Brooks L, Durbin R, Garrison E, Kang H, Korbel J . A global reference for human genetic variation. Nature. 2015; 526(7571):68-74. PMC: 4750478. DOI: 10.1038/nature15393. View

13.

Mitchell J, Li N, Weinhold N, Forsti A, Ali M, van Duin M . Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. Nat Commun. 2016; 7:12050. PMC: 4932178. DOI: 10.1038/ncomms12050. View

14.

Christensen K, MacKenzie R . Mitochondrial methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetases. Vitam Horm. 2008; 79:393-410. DOI: 10.1016/S0083-6729(08)00414-7. View

15.

Swaminathan B, Thorleifsson G, Joud M, Ali M, Johnsson E, Ajore R . Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. Nat Commun. 2015; 6:7213. PMC: 4455110. DOI: 10.1038/ncomms8213. View

16.

Ziv E, Dean E, Hu D, Martino A, Serie D, Curtin K . Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients. Nat Commun. 2015; 6:7539. PMC: 4656791. DOI: 10.1038/ncomms8539. View