Conservation of Structure in the Human Gene Encoding Argininosuccinate Synthetase and the ArgG Genes of the Archaebacteria Methanosarcina Barkeri MS and Methanococcus Vannielii

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1988 Jul 1

PMID 3133361

Citations 7

Authors

C J Morris

J N Reeve

Affiliations

Soon will be listed here.

Abstract

The DNA sequences of the argG genes of Methanosarcina barkeri MS and Methanococcus vannielii were determined. The polypeptide products of these methanogen genes have amino acid sequences which are 50% identical to each other and 38% identical to the amino acid sequence encoded by the exons of the human argininosuccinate synthetase gene. Introns in the human chromosomal gene separate regions which encode amino acids conserved in both the archaebacterial and human gene products. An open reading frame immediately upstream of argG in Methanosarcina barkeri MS codes for an amino acid sequence which is 45 and 31% identical to the sequences of the large subunits of carbamyl phosphate synthetase in Escherichia coli and Saccharomyces cerevisiae, respectively. If this gene encodes carbamyl phosphate synthetase in Methanosarcina barkeri, this is the first example, in an archaebacterium, of physical linkage of genes that encode enzymes which catalyze reactions in the same amino acid biosynthetic pathway.

Citing Articles

Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis.

Lakhal-Naouar I, Jardim A, Strasser R, Luo S, Kozakai Y, Nakhasi H PLoS Negl Trop Dis. 2012; 6(10):e1849.

PMID: 23094117 PMC: 3475689. DOI: 10.1371/journal.pntd.0001849.

Archaea and the prokaryote-to-eukaryote transition.

Brown J, Doolittle W Microbiol Mol Biol Rev. 1997; 61(4):456-502.

PMID: 9409149 PMC: 232621. DOI: 10.1128/mmbr.61.4.456-502.1997.

Sequence and transcript analysis of a novel Methanosarcina barkeri methyltransferase II homolog and its associated corrinoid protein homologous to methionine synthase.

Paul L, Krzycki J J Bacteriol. 1996; 178(22):6599-607.

PMID: 8932317 PMC: 178547. DOI: 10.1128/jb.178.22.6599-6607.1996.

Evolutionary relationships of the carbamoylphosphate synthetase genes.

van den Hoff M, Jonker A, Beintema J, Lamers W J Mol Evol. 1995; 41(6):813-32.

PMID: 8587126 DOI: 10.1007/BF00173161.

Molecular cloning and characterization of the cDNA coding for the biotin-containing subunit of 3-methylcrotonoyl-CoA carboxylase: identification of the biotin carboxylase and biotin-carrier domains.

Song J, Wurtele E, Nikolau B Proc Natl Acad Sci U S A. 1994; 91(13):5779-83.

PMID: 8016064 PMC: 44080. DOI: 10.1073/pnas.91.13.5779.

References

Maxam A, Gilbert W . Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 1980; 65(1):499-560. DOI: 10.1016/s0076-6879(80)65059-9. View

Thomm M, Sherf B, Reeve J . RNA polymerase-binding and transcription initiation sites upstream of the methyl reductase operon of Methanococcus vannielii. J Bacteriol. 1988; 170(4):1958-61. PMC: 211058. DOI: 10.1128/jb.170.4.1958-1961.1988. View

Nakamura Y, Uchida H . Isolation of conditionally lethal amber mutations affecting synthesis of the nusA protein of Escherichia coli. Mol Gen Genet. 1983; 190(2):196-203. DOI: 10.1007/BF00330640. View

Nyunoya H, LUSTY C . The carB gene of Escherichia coli: a duplicated gene coding for the large subunit of carbamoyl-phosphate synthetase. Proc Natl Acad Sci U S A. 1983; 80(15):4629-33. PMC: 384097. DOI: 10.1073/pnas.80.15.4629. View

Wood A, Redborg A, Cue D, Whitman W, Konisky J . Complementation of argG and hisA mutations of Escherichia coli by DNA cloned from the archaebacterium Methanococcus voltae. J Bacteriol. 1983; 156(1):19-29. PMC: 215046. DOI: 10.1128/jb.156.1.19-29.1983. View

LUSTY C, Widgren E, Broglie K, Nyunoya H . Yeast carbamyl phosphate synthetase. Structure of the yeast gene and homology to Escherichia coli carbamyl phosphate synthetase. J Biol Chem. 1983; 258(23):14466-77. View

Freytag S, Bock H, Beaudet A, OBrien W . Molecular structures of human argininosuccinate synthetase pseudogenes. Evolutionary and mechanistic implications. J Biol Chem. 1984; 259(5):3160-6. View

Freytag S, Beaudet A, Bock H, OBrien W . Molecular structure of the human argininosuccinate synthetase gene: occurrence of alternative mRNA splicing. Mol Cell Biol. 1984; 4(10):1978-84. PMC: 369014. DOI: 10.1128/mcb.4.10.1978-1984.1984. View

Cue D, Beckler G, Reeve J, Konisky J . Structure and sequence divergence of two archaebacterial genes. Proc Natl Acad Sci U S A. 1985; 82(12):4207-11. PMC: 397965. DOI: 10.1073/pnas.82.12.4207. View

10.

Sharp P . On the origin of RNA splicing and introns. Cell. 1985; 42(2):397-400. DOI: 10.1016/0092-8674(85)90092-3. View

11.

Muller B, Allmansberger R, Klein A . Termination of a transcription unit comprising highly expressed genes in the archaebacterium Methanococcus voltae. Nucleic Acids Res. 1985; 13(18):6439-45. PMC: 321969. DOI: 10.1093/nar/13.18.6439. View

12.

Darnell J, Doolittle W . Speculations on the early course of evolution. Proc Natl Acad Sci U S A. 1986; 83(5):1271-5. PMC: 323057. DOI: 10.1073/pnas.83.5.1271. View

13.

Wich G, Hummel H, Jarsch M, BAR U, Bock A . Transcription signals for stable RNA genes in Methanococcus. Nucleic Acids Res. 1986; 14(6):2459-79. PMC: 339676. DOI: 10.1093/nar/14.6.2459. View

14.

Gilbert W, Marchionni M, McKnight G . On the antiquity of introns. Cell. 1986; 46(2):151-3. DOI: 10.1016/0092-8674(86)90730-0. View

15.

Beckler G, Reeve J . Conservation of primary structure in the hisI gene of the archaebacterium, Methanococcus vannielii, the eubacterium Escherichia coli, and the eucaryote Saccharomyces cerevisiae. Mol Gen Genet. 1986; 204(1):133-40. DOI: 10.1007/BF00330200. View

16.

Davis R . Compartmental and regulatory mechanisms in the arginine pathways of Neurospora crassa and Saccharomyces cerevisiae. Microbiol Rev. 1986; 50(3):280-313. PMC: 373072. DOI: 10.1128/mr.50.3.280-313.1986. View

17.

Cunin R, Glansdorff N, PIERARD A, Stalon V . Biosynthesis and metabolism of arginine in bacteria. Microbiol Rev. 1986; 50(3):314-52. PMC: 373073. DOI: 10.1128/mr.50.3.314-352.1986. View

18.

Jones W, Nagle Jr D, Whitman W . Methanogens and the diversity of archaebacteria. Microbiol Rev. 1987; 51(1):135-77. PMC: 373095. DOI: 10.1128/mr.51.1.135-177.1987. View

19.

Weil C, Beckler G, Reeve J . Structure and organization of the hisA gene of the thermophilic archaebacterium Methanococcus thermolithotrophicus. J Bacteriol. 1987; 169(10):4857-60. PMC: 213870. DOI: 10.1128/jb.169.10.4857-4860.1987. View

20.

Brown J, Thomm M, Beckler G, Frey G, Stetter K, Reeve J . An archaebacterial RNA polymerase binding site and transcription initiation of the hisA gene in Methanococcus vannielii. Nucleic Acids Res. 1988; 16(1):135-50. PMC: 334617. DOI: 10.1093/nar/16.1.135. View